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聚丙烯酸树脂Ⅳ

聚丙烯酸树脂Ⅳ名称

[ CAS 号 ]:
24938-16-7

[ 中文名 ]:
聚丙烯酸树脂Ⅳ

[ 英文名 ]:
Amino methacrylate copolymer

[英文别名 ]:

Basic butylated methacrylate copolyme

聚丙烯酸树脂Ⅳ物理化学性质

[ 沸点 ]:
187ºC at 760mmHg

[ 分子式 ]:
C₂₁H₃₇NO₆

[ 分子量 ]:
399.522

[ 闪点 ]:
>250℃

[ 精确质量 ]:
399.262085

[ PSA ]:
82.14000

[ LogP ]:
3.30860

[ 外观性状 ]:
无色至黄色粉末

[ 储存条件 ]:
室温

聚丙烯酸树脂Ⅳ毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OZ3688000

CHEMICAL NAME :: Methacrylic acid, butyl ester, polymer with 2-(dimethylamino)ethyl methacrylate and methyl methacrylate

CAS REGISTRY NUMBER :: 24938-16-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

REFERENCE :: APHGAO Acta Pharmaceutica Hungarica. (Kultura, POB 149, H-1389 Budapest, Hungary) 1953- Adopts V.24 in 1955. Volume(issue)/page/year: 56,97,1986

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聚丙烯酸树脂Ⅳ安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

聚丙烯酸树脂Ⅳ文献

Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions.

Chem. Pharm. Bull. 60(11) , 1468-73, (2012)

In this study, amorphous solid dispersions containing dutasteride and various excipients, manufactured by spray-drying processes, were characterized to determine the effects on their ability to form s...

Effect of aminoalkyl methacrylate copolymer E/HCl on in vivo absorption of poorly water-soluble drug.

Drug Dev. Ind. Pharm. 39(11) , 1698-705, (2013)

This study aimed to investigate in vivo absorption of tacrolimus formulated as a solid dispersion using Eudragit E®/HCl (E-SD). E-SD is an aminoalkyl methacrylate copolymer that can be dissolved under...

Eudragit E as excipient for production of granules and tablets from Phyllanthus niruri L spray-dried extract.

AAPS PharmSciTech 8(2) , Article 34, (2007)

The aim of this study was to investigate the feasibility of using Eudragit E as a granulating agent for a spray-dried extract from Phyllanthus niruri to obtain tablets containing a high dose of this p...

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