1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐

1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐用途

1-(3-二甲氨基丙基)-3-乙基碳化二亚胺盐酸盐是一种碳化二亚胺试剂,可形成核酸和具有酰胺键的化合物。1-(3-二甲氨基丙基)-3-乙基碳化二亚胺盐酸盐作为凝聚剂和脱水剂加速酯、酰胺和肽的形成反应,通常用于多核苷酸合成、脱水、乳糖化和酯化[1][2]。

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1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐名称

[ CAS 号 ]:
25952-53-8

[ 中文名 ]:
1-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐

[ 英文名 ]:
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride

[中文别名 ]:

[英文别名 ]:

EDC HCL
EDAC,Hydrochloride
EDCI
EINECS 217-579-2
EDAP
MFCD00044916
EDC.HCl
EDC hydrochloride
edac hcl
wsc hcl

1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

1-(3-二甲氨基丙基)-3-乙基碳化二亚胺盐酸盐(EDC.HCl)是在水介质中形成酰胺键(肽键)的非常有用的试剂[1]。1-(3-二甲氨基丙基)-3-乙基碳化二亚胺盐酸盐(EDC•HCl)广泛用于制备用于胆固醇生物传感器的聚苯胺碳纳米管,用于HPLC的脂肪族胺柱前衍生,用于DNA研究的分子信标形成,用于钙检测的传感器制备,羧酸的荧光测定和肽的固相微序列测定[2]。1-(3-二甲氨基丙基)-3-乙基碳化二亚胺盐酸盐(EDC•HCl)是一种氨基醛脱氢酶(AMADH)抑制剂,而其对谷氨酸脱羧酶(GAD)的抑制作用不显著[3]。

[参考文献]

[1]. Kunihiko Seno, et al. Spectrophotometric determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow injection analysis. Anal Sci. 2008 Apr;24(4):505-8.

[2]. Kunihiko Seno, et al. Determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow-injection analysis based on a specific condensation reaction between malonic acid and ethylenediamine. Anal Sci. 2009 Mar;25(3):389-93.

[3]. Runqiang Yang, et al. AMADH inhibitor optimization and its effects on GABA accumulation in soybean sprouts under NaCl-CaCl 2 treatment. 3 Biotech. 2019 May;9(5):184.

1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐物理化学性质

[ 密度 ]:
0.877 g/mL at 20 °C(lit.)

[ 沸点 ]:
269.1ºC at 760 mmHg

[ 熔点 ]:
110-115 °C(lit.)

[ 分子式 ]:
C₈H₁₈ClN₃

[ 分子量 ]:
191.70

[ 闪点 ]:
107.9ºC

[ 精确质量 ]:
191.118927

[ PSA ]:
27.96000

[ LogP ]:
1.93390

[ 外观性状 ]:
白色至灰白色粉末

[ 蒸汽压 ]:
0.171mmHg at 25°C

[ 折射率 ]:
n20/D 1.461

[ 储存条件 ]:
−20°C

[ 稳定性 ]:
Stable, but sensitive to moisture. Incompatible with strong acids, strong oxidizing agents, moisture.

[ 水溶解性 ]:
Soluble

1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐MSDS

详细MSDS(安全技术说明书)

1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H315-H318-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S37/39

[ 危险品运输编码 ]:
UN 2735 8/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
FF2200000

[ 海关编码 ]:
29252000

1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐上下游产品

1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐上游产品

1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐下游产品

1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐海关

[ 海关编码 ]: 2925290090

[ 中文概述 ]:
2925290090 其他亚胺及其衍生物，以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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