Acetamide,2-fluoro-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-,(S)- (9CI)
名称
[ CAS 号 ]:
26195-68-6
[ 英文名 ]:
Acetamide,2-fluoro-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-,(S)- (9CI)
[英文别名 ]:
- COLCHICINE,17-FLUORO
- 17-Fluorocolchicine
- Fluorocolchicine
物理化学性质
[ 密度 ]:
1.29g/cm3
[ 沸点 ]:
733.2ºC at 760mmHg
[ 分子式 ]:
C22H24FNO6
[ 分子量 ]:
417.42700
[ 闪点 ]:
397.2ºC
[ 精确质量 ]:
417.15900
[ PSA ]:
83.09000
[ LogP ]:
3.21210
[ 蒸汽压 ]:
2.34E-21mmHg at 25°C
[ 折射率 ]:
1.574
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GH0887000
- CHEMICAL NAME :
- Colchicine, 17-fluoro-
- CAS REGISTRY NUMBER :
- 26195-68-6
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C22-H24-F-N-O6
- MOLECULAR WEIGHT :
- 417.47
- WISWESSER LINE NOTATION :
- L B677 MV&T&J CO1 DO1 EO1 JMV1F NO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 852 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981
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CAS号[26195-68-6]化源网提供[Acetamide,2-fluoro-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-,(S)- (9CI)]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版：Acetamide,2-fluoro-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-,(S)- (9CI)
标题：26195-68-6_CAS号:26195-68-6_Acetamide,2-fluoro-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-,(S)- (9CI) - 化源网 地址：https://m.chemsrc.com/mip/cas/26195-68-6_677767.html