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N4-苯甲酰胞嘧啶

N4-苯甲酰胞嘧啶用途

医药中间体

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N4-苯甲酰胞嘧啶名称

[ CAS 号 ]:
26661-13-2

[ 中文名 ]:
N4-苯甲酰基胞嘧啶

[ 英文名 ]:
N4-Benzoylcytosine

[中文别名 ]:

[英文别名 ]:

N-(2-oxohydropyrimidin-4-yl)benzamide
N4-Benzoylcytosine
N6-benzoylcytosine
N3-benzoylcytosine
N-(2-Oxo-1,2-dihydro-4-pyrimidinyl)benzamide
N-(2-Oxo-1,2-dihydropyrimidin-4-yl)benzamide
MFCD00239434
N-(1,2-dihydro-2-oxopyrimidin-4-yl)-benzamide
N4-Benzoyl Cytosine
N-benzoylcytosine

N4-苯甲酰胞嘧啶物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 熔点 ]:
>300 °C (dec.)(lit.)

[ 分子式 ]:
C₁₁H₉N₃O₂

[ 分子量 ]:
215.208

[ 精确质量 ]:
215.069473

[ PSA ]:
74.85000

[ LogP ]:
0.42

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 折射率 ]:
1.652

[ 储存条件 ]:
室温，干燥，密封

N4-苯甲酰胞嘧啶MSDS

N4-苯甲酰胞嘧啶安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H332-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R20/22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

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N4-苯甲酰胞嘧啶文献

Synthesis and biological evaluation of 3'-C-ethynyl and 3'-C-(1,4-disubstituted-1,2,3-triazolo) double-headed pyranonucleosides.

Med. Chem. 8(3) , 320-9, (2012)

A novel series of 3'-C-ethynyl and 3'-C-(1,4-disubstituted-1,2,3-triazolo) double-headed pyranonucleosides has been designed and synthesized. Reaction of 3-keto glucoside 1 with ethynyl magnesium brom...

Nucleosides and nucleotides. 232. Synthesis of 2'-C-methyl-4'-thiocytidine: unexpected anomerization of the 2'-keto-4'-thionucleoside precursor.

Nucleosides Nucleotides Nucleic Acids 24(10-12) , 1789-800, (2005)

The synthesis of 2'-C-methyl-4'-thiocytidine (16) is described. Since the 2'-keto-4'-thiocytidine derivative 2beta unexpectedly isomerized to 2alpha and the methylation of 2beta proceeded predominantl...

Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2', 3'-unsaturated L-nucleosides.

J. Med. Chem. 42(7) , 1320-8, (1999)

The synthesis of L-nucleoside analogues containing 2'-vinylic fluoride was accomplished by direct condensation method, and their anti-HIV and anti-HBV activities were evaluated in vitro. The key inter...

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