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酰基-2-油酰基1-棕榈酰-SN-甘油-3-磷酸乙醇胺

用途

1-Palmitoyl-2-oleoyl-sn-glycero-3-PE 是一种磷脂,可用于药物递送研究。

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名称

[ CAS 号 ]:
26662-94-2

[ 中文名 ]:
1-棕榈酰基-2-油酰基-sn-甘油-3-磷酸乙醇胺

[ 英文名 ]:
2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamine

[英文别名 ]:

MFCD00042829

生物活性

[ 描述 ]:

1-Palmitoyl-2-oleoyl-sn-glycero-3-PE 是一种磷脂,可用于药物递送研究。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Álvarez-Benedicto E, et al. Optimization of phospholipid chemistry for improved lipid nanoparticle (LNP) delivery of messenger RNA (mRNA). Biomater Sci. 2022 Jan 18;10(2):549-559.

物理化学性质

[ 熔点 ]:
24.7 °C (lit.)

[ 分子式 ]:
C₃₉H₇₆NO₈P

[ 分子量 ]:
717.99600

[ 精确质量 ]:
717.53100

[ PSA ]:
144.19000

[ LogP ]:
11.75280

[ 外观性状 ]:
白色粉末

[ 储存条件 ]:
20°C

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 风险声明 (欧洲) ]:
22-38-40-48/20/22

[ 安全声明 (欧洲) ]:
36/37

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Interactions of a non-fluorescent fluoroquinolone with biological membrane models: A multi-technique approach.

Int. J. Pharm. 495 , 761-70, (2015)

Fluoroquinolones are antibiotics which act by penetrating into bacterial cells and inhibiting enzymes related to DNA replication, and metal complexes of these drugs have recently been investigated as ...

Attractors in Sequence Space: Peptide Morphing by Directed Simulated Evolution.

Mol. Inform. 34 , 709-714, (2016)

Identification of carbonylated lipids from different phospholipid classes by shotgun and LC-MS lipidomics.

Anal. Bioanal. Chem 407 , 5161-73, (2015)

Oxidized lipids play a significant role in the pathogenesis of numerous oxidative stress-related human disorders, such as atherosclerosis, obesity, inflammation, and autoimmune diseases. Lipid peroxid...

更多文献

酰基-2-油酰基1-棕榈酰-SN-甘油-3-磷酸乙醇胺

用途

名称

生物活性

物理化学性质

安全信息

文献

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