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邻苯二甲酸二异癸酯

邻苯二甲酸二异癸酯用途

【用途一】
用作色谱固定液。
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邻苯二甲酸二异癸酯名称

[ CAS 号 ]:
26761-40-0

[ 中文名 ]:
邻苯二甲酸二异癸酯

[ 英文名 ]:
Reomol DiDP

[中文别名 ]:

[英文别名 ]:

邻苯二甲酸二异癸酯物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
425.8±13.0 °C at 760 mmHg

[ 熔点 ]:
235ºC

[ 分子式 ]:
C28H46O4

[ 分子量 ]:
446.662

[ 闪点 ]:
227.6±9.3 °C

[ 精确质量 ]:
446.339600

[ PSA ]:
52.60000

[ LogP ]:
10.83

[ 外观性状 ]:
无色液体

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.487

[ 储存条件 ]:
通风低温干燥,与库房食品原料分开存放

[ 水溶解性 ]:
水溶性:不溶;水溶解度:0.28 mg/l   24 °C

邻苯二甲酸二异癸酯MSDS

邻苯二甲酸二异癸酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TI1270000
CHEMICAL NAME :
Phthalic acid, diisodecyl ester
CAS REGISTRY NUMBER :
26761-40-0
LAST UPDATED :
199806
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C28-H46-O4
MOLECULAR WEIGHT :
446.74

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
64 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 3,131,1973
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>130 mg/m3/6H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001)
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>130 mg/m3/6H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001)
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
22500 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 3,61,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>3160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001)
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
>130 mg/m3/6H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001) ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
58800 mg/kg/14W-C
TOXIC EFFECTS :
Liver - changes in liver weight
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 3,131,1973 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
10 gm/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 35,501,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-SWEDEN:TWA 3 mg/m3;STEL 5 mg/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83278 No. of Facilities: 1017 (estimated) No. of Industries: 18 No. of Occupations: 41 No. of Employees: 21856 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83278 No. of Facilities: 2962 (estimated) No. of Industries: 53 No. of Occupations: 57 No. of Employees: 80441 (estimated) No. of Female Employees: 31734 (estimated)
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邻苯二甲酸二异癸酯安全信息

[ 符号 ]:

GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H410

[ 警示性声明 ]:
P273-P501

[ 个人防护装备 ]:
Eyeshields;Gloves

[ 危害码 (欧洲) ]:
N

[ 风险声明 (欧洲) ]:
50/53

[ 安全声明 (欧洲) ]:
23-24/25

[ 危险品运输编码 ]:
UN 3082 9 / PGIII

[ WGK德国 ]:
1

[ RTECS号 ]:
TI1270000

[ 海关编码 ]:
2917349000

邻苯二甲酸二异癸酯海关

[ 海关编码 ]: 2917349000

[ 中文概述 ]:
2917349000 其他邻苯二甲酸酯。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 对苯二甲酸请注明4-CBA值, 对苯二甲酸请注明P-TL酸值, 对苯二甲酸请注明色度, 对苯二甲酸请注明水分

[ Summary ]:
2917349000 other esters of orthophthalic acid。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

邻苯二甲酸二异癸酯文献

Effects of endocrine disruptors on dehydroepiandrosterone sulfotransferase and enzymes involved in PAPS synthesis: genomic and nongenomic pathways.

Environ. Health Perspect. 115 Suppl 1 , 51-4, (2007)

Sulfation plays an important role both in detoxification and in the control of steroid activity. Studies in rodents have shown that the conversion of dehydroepiandrosterone (DHEA) to DHEA-sulfate is i...

Adjuvant effect of di-n-butyl-, di-n-octyl-, di-iso-nonyl- and di-iso-decyl phthalate in a subcutaneous injection model using BALB/c mice.

Pharmacol. Toxicol. 91(5) , 264-72, (2002)

During the last decades, the prevalence of the allergic airway diseases, asthma and rhinitis, has increased world-wide. Introduction of environmental chemicals with adjuvant effect may play a role in ...

Effects of phthalates on the human corneal endothelial cell line B4G12.

Int. J. Toxicol. 31(4) , 364-71, (2012)

Phthalates are industrial chemicals used in many cosmetics. We evaluated an in vitro model for eye irritancy testing using the human corneal endothelial cell line B4G12. Cell proliferation and toxicit...


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