奥沙美辛

奥沙美辛用途

Oxametacin is a anti-inflammatory compound used with care in anticoagulated patients. It has analgesic, antipyretic and anti-inflammatory properties comparable to those of indomethacin.

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奥沙美辛名称

[ CAS 号 ]:
27035-30-9

[ 中文名 ]:
奥沙美辛

[ 英文名 ]:
Oxametacin

[英文别名 ]:

Oxametacinum [INN-Latin]
Oxametacine [INN-French]
Oxametacin
Oxametacin [INN]
Acido indoxamico [Italian]
Indoxamic acid
Oxametacine
Oxametacina [INN-Spanish]
Oxamethacin
Flogar

奥沙美辛物理化学性质

[ 密度 ]:
1.35g/cm3

[ 分子式 ]:
C₁₉H₁₇ClN₂O₄

[ 分子量 ]:
372.80200

[ 精确质量 ]:
372.08800

[ PSA ]:
80.56000

[ LogP ]:
3.73900

[ 折射率 ]:
1.63

奥沙美辛毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL3668500

CHEMICAL NAME :: Indole-3-acetohydroxamic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-

CAS REGISTRY NUMBER :: 27035-30-9

BEILSTEIN REFERENCE NO. :: 0497721

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H17-Cl-N2-O4

MOLECULAR WEIGHT :: 372.83

WISWESSER LINE NOTATION :: T56 BNJ BVR DG& C1 D1VMQ GO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 78 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 92 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

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奥沙美辛安全信息

[ 海关编码 ]:
2933990090

奥沙美辛合成路线

详细合成路线

奥沙美辛上下游产品

奥沙美辛上游产品

奥沙美辛下游产品

奥沙美辛海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%