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4-氟-DL-谷氨酸

4-氟-DL-谷氨酸用途

4-氟-DL-谷氨酸是一种谷氨酸衍生物[1]。

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4-氟-DL-谷氨酸名称

[ CAS 号 ]:
2708-77-2

[ 中文名 ]:
4-氟-DL-谷氨酸

[ 英文名 ]:
DL-4-FluoroglutaMic acid

[中文别名 ]:

(±)-2-氨基-4-氟戊二酸

[英文别名 ]:

4-Fluoro-2-aminopentanedioic acid
2-Amino-4-fluoropentane-1,5-dioic acid
EINECS 220-302-8
4-Fluoro-Glutamic Acid
threo-4-fluoroglutamic acid
D,L-erythro,threo-4-fluoroglutamic acid
H-4-F-DL-Glu-OH
erythro-4-fluoroglutamic acid
DL-erythro-4-fluoroglutamic acid
DL-4-FLUOROGLUTAMIC ACID

4-氟-DL-谷氨酸生物活性

[ 描述 ]:

4-氟-DL-谷氨酸是一种谷氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

4-氟-DL-谷氨酸物理化学性质

[ 密度 ]:
1.498 g/cm3

[ 沸点 ]:
342.4ºC at 760 mmHg

[ 熔点 ]:
185°C (dec.)

[ 分子式 ]:
C₅H₈FNO₄

[ 分子量 ]:
165.12000

[ 闪点 ]:
160.9ºC

[ 精确质量 ]:
165.04400

[ PSA ]:
100.62000

[ 蒸汽压 ]:
1.37E-05mmHg at 25°C

[ 折射率 ]:
1.491

[ 储存条件 ]:
室温

4-氟-DL-谷氨酸MSDS

4-氟-DL-谷氨酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2922499990

4-氟-DL-谷氨酸合成路线

4-氟-DL-谷氨酸上下游产品

4-氟-DL-谷氨酸上游产品

4-氟-DL-谷氨酸下游产品

4-氟-DL-谷氨酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

4-氟-DL-谷氨酸文献

4-[18F]fluoroglutamic acid (BAY 85-8050), a new amino acid radiotracer for PET imaging of tumors: synthesis and in vitro characterization.

J. Med. Chem. 54(1) , 406-10, (2011)

There is a high demand for tumor specific PET tracers in oncology imaging. Besides glucose, certain amino acids also serve as energy sources and anabolic precursors for tumors. Therefore, (18)F-labele...

Mutations of the Corynebacterium glutamicum NCgl1221 gene, encoding a mechanosensitive channel homolog, induce L-glutamic acid production.

Appl. Environ. Microbiol. 73(14) , 4491-8, (2007)

Corynebacterium glutamicum is a biotin auxotroph that secretes L-glutamic acid in response to biotin limitation; this process is employed in industrial L-glutamic acid production. Fatty acid ester sur...

Vitamin K-dependent carboxylation. Study of the hydrogen abstraction stereochemistry with gamma-fluoroglutamic acid-containing peptides.

J. Biol. Chem. 258(13) , 7897-9, (1983)

Two pentapeptides Phe-Leu-X-Glu-Val where X is either the L-threo-gamma-fluoroglutamic acid or the L-erythro-isomer have been synthesized and tested as substrates in the vitamin K-dependent carboxylat...

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