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5-氟色胺盐酸盐

5-氟色胺盐酸盐名称

[ CAS 号 ]:
2711-58-2

[ 中文名 ]:
5-氟色胺盐酸盐

[ 英文名 ]:
5-Fluorotryptamine hydrochloride

[中文别名 ]:

[英文别名 ]:

5-Fluorotryptaminehydrochloride
2-(5-Fluoro-1H-indol-3-yl)ethanamine
1H-Indole-3-ethanamine, 5-fluoro-
5-Fluorotryptamine hydrochloride
2-(5-fluoro-1H-indol-3-yl)ethanamine,hydrochloride
EINECS 220-307-5
MFCD00051081

5-氟色胺盐酸盐物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
346.0±27.0 °C at 760 mmHg

[ 熔点 ]:
277-283

[ 分子式 ]:
C₁₀H₁₂ClFN₂

[ 分子量 ]:
214.667

[ 闪点 ]:
163.0±23.7 °C

[ 精确质量 ]:
214.067307

[ PSA ]:
41.81000

[ LogP ]:
1.52

[ 外观性状 ]:
灰白色结晶粉末

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.644

[ 储存条件 ]:
−20°C

5-氟色胺盐酸盐MSDS

详细MSDS(安全技术说明书)

5-氟色胺盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL4055600

CHEMICAL NAME :: Indole, 3-(2-aminoethyl)-5-fluoro-, hydrochloride

CAS REGISTRY NUMBER :: 2711-58-2

LAST UPDATED :: 199206

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H11-F-N2.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 529 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 16,200,1960

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5-氟色胺盐酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
NL4055600

[ 海关编码 ]:
2942000000

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5-氟色胺盐酸盐海关

[ 海关编码 ]: 2942000000

5-氟色胺盐酸盐文献

5-Fluorotryptamine is a partial agonist at 5-HT3 receptors, and reveals that size and electronegativity at the 5 position of tryptamine are critical for efficient receptor function.

Eur. J. Pharmacol. 580(3) , 291-7, (2008)

Antagonists, but not agonists, of the 5-HT3 receptor are useful therapeutic agents, and it is possible that partial agonists may also be potentially useful in the clinic. Here we show that 5-fluorotry...

Quantitative determination of melatonin in human plasma and cerebrospinal fluid with high-performance liquid chromatography and fluorescence detection.

Biomed. Chromatogr. 14(5) , 306-10, (2000)

A validated new and precise reversed-phase high-performance liquid chromatographic method for the determination of melatonin in human plasma and cerebrospinal fluid, with 5-fluorotryptamine as interna...

Thrombin: active-site topography.

Ann. N. Y. Acad. Sci. 485 , 80-95, (1986)

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