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(S)-2-氨基-3-(2,4,5-三羟基苯基)丙酸

(S)-2-氨基-3-(2,4,5-三羟基苯基)丙酸用途

6-羟基-L-DOPA是一种用给电子单元官能化的核酸[1]。

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(S)-2-氨基-3-(2,4,5-三羟基苯基)丙酸名称

[ CAS 号 ]:
27244-64-0

[ 中文名 ]:
左旋多巴杂质A

[ 英文名 ]:
6-Hydroxy-L-DOPA

[英文别名 ]:

L-Hydroxydopa
2,4,5-trihydroxyphenyl-L-alanine
2,4,5-trihydroxy-L-phenylalanine
2,5-Dihydroxy-L-tyrosine
L-6-Hydroxydopa
2,4,5,-trihydroxyphenylalanine
2,4,5-Trihydroxyphenylalanine,L
6-OH-DOPA
L-2,4,5-Trihydroxyphenylalanine
6-Hydroxydopa

(S)-2-氨基-3-(2,4,5-三羟基苯基)丙酸生物活性

[ 描述 ]:

6-羟基-L-DOPA是一种用给电子单元官能化的核酸[1]。

[ 相关类别 ]:

研究领域 >> 其他

[参考文献]

[1]. Enkin N, et, al. Ag nanocluster/DNA hybrids: functional modules for the detection of nitroaromatic and RDX explosives. Nano Lett. 2014 Aug 13;14(8):4918-22.

(S)-2-氨基-3-(2,4,5-三羟基苯基)丙酸物理化学性质

[ 密度 ]:
1.606g/cm3

[ 沸点 ]:
515.2ºC at 760mmHg

[ 分子式 ]:
C₉H₁₁NO₅

[ 分子量 ]:
213.19

[ 闪点 ]:
265.4ºC

[ 精确质量 ]:
213.06400

[ PSA ]:
124.01000

[ LogP ]:
0.45810

[ 外观性状 ]:
固体

[ 储存条件 ]:
2-8°C，干燥，避光

(S)-2-氨基-3-(2,4,5-三羟基苯基)丙酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY7640000

CHEMICAL NAME :: Alanine, 3-(2,4,5-trihydroxyphenyl)-, L-

CAS REGISTRY NUMBER :: 27244-64-0

LAST UPDATED :: 199206

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H11-N-O5

MOLECULAR WEIGHT :: 213.21

WISWESSER LINE NOTATION :: QVYZ1R BQ DQ EQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

DOSE :: 100 mg/kg

SEX/DURATION :: female 17 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - biochemical and metabolic

REFERENCE :: LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 17,987,1975

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(S)-2-氨基-3-(2,4,5-三羟基苯基)丙酸安全信息

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2922509090

(S)-2-氨基-3-(2,4,5-三羟基苯基)丙酸海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

(S)-2-氨基-3-(2,4,5-三羟基苯基)丙酸文献

The free radical site in pea seedling copper amine oxidase probed by resonance Raman spectroscopy and generated by photolysis of caged substrate.

FEBS Lett. 380(1-2) , 183-7, (1996)

Resonance Raman spectra were obtained of the free radical site in substrate reduced anaerobic samples of pea seedling copper amine oxidase (PSAO). The spectra differ significantly from those reported ...

Adenosine A2A receptor antagonists improve deficits in initiation of movement and sensory motor integration in the unilateral 6-hydroxydopamine rat model of Parkinson's disease.

Synapse 61 , 606-614, (2007)

Evidence obtained in rodent and primate models of Parkinson's disease (PD) and preliminary clinical trials, indicates that adenosine A(2A) receptor antagonists might represent a promising nondopaminer...

Up-regulation in expression of vesicular glutamate transporter 3 in substantia nigra but not in striatum of 6-hydroxydopamine-lesioned rats.

Neurosignals 15(5) , 238-48, (2006)

Overactivity of the glutamatergic system is suggested to be closely related to the onset and pathogenesis of Parkinson's disease. Vesicular glutamate transporters (VGLUT1, T2 and T3) are a group of gl...

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