胆甾醇聚乙二醇

胆甾醇聚乙二醇用途

Chol-PEG是一种非离子表面活性剂囊泡,可用于血液持久性药物输送系统[1][2]。

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胆甾醇聚乙二醇名称

[ 英文名 ]:
2-[[(3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13- dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[ a]phenanthren-3-yl]oxy]ethanol

胆甾醇聚乙二醇生物活性

[ 描述 ]:

Chol-PEG是一种非离子表面活性剂囊泡,可用于血液持久性药物输送系统[1][2]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Yang DB, et, al. Synthesis and application of poly(ethylene glycol)-cholesterol (Chol-PEGm) conjugates in physicochemical characterization of nonionic surfactant vesicles. Colloids Surf B Biointerfaces. 2008 Jun 1;63(2):192-9.

[2]. Barnard A, et, al. Effects of a PEG additive on the biomolecular interactions of self-assembled dendron nanostructures. Org Biomol Chem. 2012 Nov 14;10(42):8403-9.

胆甾醇聚乙二醇物理化学性质

[ 密度 ]:
1g/cm3

[ 沸点 ]:
524.9ºC at 760mmHg

[ 分子式 ]:
C₂₉H₅₀O₂

[ 分子量 ]:
430.70600

[ 闪点 ]:
210.5ºC

[ 精确质量 ]:
430.38100

[ PSA ]:
29.46000

[ LogP ]:
7.40530

胆甾醇聚乙二醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MD0400000

CHEMICAL NAME :: Glycols, polyethylene, monocholesteryl ether

CAS REGISTRY NUMBER :: 27321-96-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Human - man

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9020 No. of Facilities: 19 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 93 (estimated) No. of Female Employees: 56 (estimated)