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替洛隆

替洛隆名称

[ CAS 号 ]:
27591-97-5

[ 中文名 ]:
乙胺芴酮

[ 英文名 ]:
Tilorone

[中文别名 ]:

[英文别名 ]:

UNII-O6W7VEW6KS
Tilorone
Amixin IC
2,7-Bis-DEAE-fluorenone
Tilorone base
Tilorone hydrochloride
2,7-Bis[2-(diethylamino)ethoxy]-9H-fluoren-9-one
9H-Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]-
Bis-DEAE-fluorenone
9H-Fluoren-9-one, 2,7-bis(2-(diethylamino)ethoxy)-

替洛隆物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
552.3±50.0 °C at 760 mmHg

[ 分子式 ]:
C₂₅H₃₄N₂O₃

[ 分子量 ]:
410.549

[ 闪点 ]:
287.8±30.1 °C

[ 精确质量 ]:
410.256958

[ PSA ]:
42.01000

[ LogP ]:
5.25

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.564

[ 储存条件 ]:
-20°C

替洛隆毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LL8990000

CHEMICAL NAME :: 9H-Fluoren-9-one, 2,7-bis(2-(diethylamino)ethoxy)-

CAS REGISTRY NUMBER :: 27591-97-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C25-H34-N2-O3

MOLECULAR WEIGHT :: 410.61

WISWESSER LINE NOTATION :: L B656 HVJ EO2N2&2 KO2N2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1780 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 121 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Immunological Including Allergic - increased immune response Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 100 umol/L

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 11,91,1975

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替洛隆

替洛隆名称

替洛隆物理化学性质

替洛隆毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

替洛隆合成路线

详细合成路线

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