福莫可他

福莫可他名称

[ 英文名 ]:
Pregna-3,5-diene-6-carboxaldehyde,21-(acetyloxy)-3-(2-chloroethoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-20-oxo-,(11b,16a)-

[英文别名 ]:

Cortocin F
DeflaMin
Fluoroformylon
Fluderma
Cutisterol
FluoforMylon
FI-6341
Deflamene
formocortal

福莫可他物理化学性质

[ 密度 ]:
1.33g/cm3

[ 沸点 ]:
683.7ºC at 760mmHg

[ 分子式 ]:
C₂₉H₃₈ClFO₈

[ 分子量 ]:
569.05900

[ 闪点 ]:
367.3ºC

[ 精确质量 ]:
568.22400

[ PSA ]:
108.36000

[ LogP ]:
3.96280

[ 蒸汽压 ]:
1.21E-21mmHg at 25°C

[ 折射率 ]:
1.564

福莫可他毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU3460000

CHEMICAL NAME :: Pregna-3,5-diene-6-carboxaldehyde, 3-(2-chloroethoxy)-9-fluoro-11-beta,16-alpha,17,21- tetrahydroxy-20-oxo-, cyclic 16,17-acetal with acetone, 21-acetate

CAS REGISTRY NUMBER :: 2825-60-7

LAST UPDATED :: 199009

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C29-H38-Cl-F-O8

MOLECULAR WEIGHT :: 569.12

WISWESSER LINE NOTATION :: T F5 E5 B666 GO IO OU QUTJ A1 BF CQ E1 FV1OV1 H1 H1 OVH RO2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 537 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 4,88,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 490 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 4,88,1971

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