2,6-Piperidinedione,4-[(2R)-2-[(1S,3S,5R)-5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-
名称
[ CAS 号 ]:
2885-39-4
[ 英文名 ]:
2,6-Piperidinedione,4-[(2R)-2-[(1S,3S,5R)-5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-
[英文别名 ]:
- AXM
- Antibiotic from streptomyces albulus
- Streptovitacin E 73
- Cycloheximide,4-acetoxy-(E-B)
- Acetyloxycycloheximide
- Antibiotic SF-2441
- Acetoxycycloheximide
- Cycloheximide,acetoxy
物理化学性质
[ 密度 ]:
1.24g/cm3
[ 沸点 ]:
529.4ºC at 760mmHg
[ 分子式 ]:
C17H25NO6
[ 分子量 ]:
339.38400
[ 闪点 ]:
274ºC
[ 精确质量 ]:
339.16800
[ PSA ]:
109.77000
[ LogP ]:
1.05600
[ 储存条件 ]:
库房通风低温干燥,与氧化剂、食品添加剂、酸类分开存放
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MA5075000
- CHEMICAL NAME :
- Glutarimide, 3-(2-hydroxy-2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexy l)ethyl)-, 5-acetate
- CAS REGISTRY NUMBER :
- 2885-39-4
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C17-H25-N-O6
- MOLECULAR WEIGHT :
- 339.43
- WISWESSER LINE NOTATION :
- T6VMVTJ EYQ1- BL6VTJ DOV1 D1 F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 158 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 170 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 190 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 19 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 920 ug/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - coma Lungs, Thorax, or Respiration - other changes
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human HeLa cell
- DOSE/DURATION :
- 1 umol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 14,205,1965
合成路线
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CAS号[2885-39-4]化源网提供[2,6-Piperidinedione,4-[(2R)-2-[(1S,3S,5R)-5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版：2,6-Piperidinedione,4-[(2R)-2-[(1S,3S,5R)-5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-
标题：2885-39-4_CAS号:2885-39-4_2,6-Piperidinedione,4-[(2R)-2-[(1S,3S,5R)-5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]- - 化源网 地址：https://m.chemsrc.com/mip/cas/2885-39-4_961315.html