< 生产厂家价格 >

S-Methylglutathione

S-Methylglutathione用途

S-Methylglutathione 是一种 S 取代的谷胱甘肽,一种比 GSH 更强的亲核试剂 (nucleophile)。S-Methylglutathione 对乙二醛酶 1 (glyoxalase 1) 有抑制作用。

点击显示

S-Methylglutathione名称

[ CAS 号 ]:
2922-56-7

[ 中文名 ]:
S-甲基谷胱甘肽

[ 英文名 ]:
S-Methyl glutathione

[英文别名 ]:

S-Methylglutathione生物活性

[ 描述 ]:

S-Methylglutathione 是一种 S 取代的谷胱甘肽,一种比 GSH 更强的亲核试剂 (nucleophile)。S-Methylglutathione 对乙二醛酶 1 (glyoxalase 1) 有抑制作用。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

S-甲基谷胱甘肽(GS-Me)比GSH具有更强的亲核性,这是由甲基的更积极的诱导作用合理化的[1]。

[参考文献]

[1]. Foye WO, et al. Synthesis and evaluation of N-alkanoyl-S-benzyl-L-cysteinylglutamic acid esters as glyoxalase I inhibitors and anticancer agents. J Pharm Sci. 1984 Apr;73(4):559-61.

[2]. Milos I. Djuran,et al. Reactivity of chloro- and aqua(diethylenetriamine)platinum(II) ions with glutathione, S-methylglutathione, and guanosine 5'-monophosphate in relation to the antitumor activity and toxicity of platinum complexes. Inorg. Chem. 1991, 30, 12, 2648–2652

S-Methylglutathione物理化学性质

[ 分子式 ]:
C₁₁H₁₉N₃O₆S

[ 分子量 ]:
321.35000

[ 精确质量 ]:
321.09900

[ PSA ]:
191.10000

[ LogP ]:
0.60800

[ 蒸汽压 ]:
1.23E-25mmHg at 25°C

[ 储存条件 ]:
2~8°C

S-MethylglutathioneMSDS

详细MSDS(安全技术说明书)

S-Methylglutathione安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3.0

[ 海关编码 ]:
2930909090

S-Methylglutathione海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

S-Methylglutathione文献

Crystallographic and thermodynamic analysis of the binding of S-octylglutathione to the Tyr 7 to Phe mutant of glutathione S-transferase from Schistosoma japonicum.

Biochemistry 44 , 1174-1183, (2005)

Glutathione S-transferases are a family of multifunctional enzymes involved in the metabolism of drugs and xenobiotics. Two tyrosine residues, Tyr 7 and Tyr 111, in the active site of the enzyme play ...

Calcium-sensing receptor-dependent activation of CREB phosphorylation in HEK293 cells and human parathyroid cells.

Am. J. Physiol. Endocrinol. Metab. 304(10) , E1097-104, (2013)

In addition to its acute effects on hormone secretion, epithelial transport, and shape change, the calcium-sensing receptor (CaSR) modulates the expression of genes that control cell survival, prolife...

3-Methyleneoxindole: an affinity label of glutathione S-transferase pi which targets tryptophan 38.

Biochemistry 40(25) , 7549-58, (2001)

The compound 3-methyleneoxindole (MOI), a photooxidation product of the plant auxin indole-3-acetic acid, functions as an affinity label of the dimeric pi class glutathione S-transferase (GST) isolate...

更多文献