1,4,8,11-四氮杂环十四烷

1,4,8,11-四氮杂环十四烷用途

Cyclam (1,4,8,11-tetraazacyclotetradecane) is an organic compound. It is a white solid that is soluble in water. The compound is notable as a macrocyclic ligand, which binds strongly to many transition metal cations. The compound was first prepared by the reaction of 1,3-dibromopropane and ethylenediamine.

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1,4,8,11-四氮杂环十四烷名称

[ CAS 号 ]:
295-37-4

[ 中文名 ]:
1,4,8,11-四氮杂环十四烷

[ 英文名 ]:
1,4,8,11-Tetraazacyclotetradecane

[中文别名 ]:

[英文别名 ]:

JM 1498
EINECS 206-039-1
Cyclam
1,4,8,11-tetrazacyclotetradecane
14-crown-4N4
1,4,8,11-Tetraazacyclotetradecane
MFCD00005105

1,4,8,11-四氮杂环十四烷物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
321.1±10.0 °C at 760 mmHg

[ 熔点 ]:
184-186 °C(lit.)

[ 分子式 ]:
C₁₀H₂₄N₄

[ 分子量 ]:
200.324

[ 闪点 ]:
153.0±14.1 °C

[ 精确质量 ]:
200.200104

[ PSA ]:
48.12000

[ LogP ]:
-0.97

[ 外观性状 ]:
白色松软的针状结晶粉末

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.426

[ 储存条件 ]:
存放于惰性气体之中;避免湿气 (吸湿)

1,4,8,11-四氮杂环十四烷MSDS

详细MSDS(安全技术说明书)

1,4,8,11-四氮杂环十四烷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XA5254800

CHEMICAL NAME :: 1,4,8,11-Tetraazacyclotetradecane

CAS REGISTRY NUMBER :: 295-37-4

BEILSTEIN REFERENCE NO. :: 0111811

LAST UPDATED :: 199806

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H24-N4

MOLECULAR WEIGHT :: 200.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 371 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Skin and Appendages - primary irritation (after topical exposure)

REFERENCE :: CMSHAF Chemosphere. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1972- Volume(issue)/page/year: 17,839,1988

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1,4,8,11-四氮杂环十四烷安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
XA5254800

[ 海关编码 ]:
2933990090

1,4,8,11-四氮杂环十四烷合成路线

详细合成路线

1,4,8,11-四氮杂环十四烷上下游产品

1,4,8,11-四氮杂环十四烷上游产品

1,4,8,11-四氮杂环十四烷下游产品

1,4,8,11-四氮杂环十四烷海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1,4,8,11-四氮杂环十四烷文献

Role of ligand to control the mechanism of nitric oxide reduction of copper(II) complexes and ligand nitrosation.

Inorg. Chem. 50(23) , 11868-76, (2011)

The nitric oxide reactivity of two copper(II) complexes, 1 and 2 with ligands L(1) and L(2), respectively, [L(1) = 5,5,7,12,12,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane, L(2) = 5,5,7-trimethyl-[...

Zn(II)-cyclam based chromogenic sensors for recognition of ATP in aqueous solution under physiological conditions and their application as viable staining agents for microorganism.

Inorg. Chem. 50(9) , 4162-70, (2011)

Two chromogenic complexes, L.Zn (where L is (E)-4-((4-(1,4,8,11-tetraazacyclotetradecan-1-ylsulfonyl)phenyl)diazenyl)-N,N-dimethylaniline) and its [2]pseudorotaxane form (α-CD.L.Zn), were found to bin...

A reversible nanoswitch as an ON-OFF photocatalyst.

Chem. Commun. (Camb.) 48(96) , 11730-2, (2012)

The two states of a new nanomechanical switch were quantitatively and reversibly populated in several subsequent switching cycles using either Cu(+) or cyclam as chemical inputs. State II was demonstr...

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