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盐酸去水吗啡

盐酸去水吗啡用途

Apomorphine Hydrochloride, also known as APL-130277 and TAK-251, is a dopamine D2 agonist used for the treatment of Parkinson's disease. Apomorphine also promotes intraneuronal amyloid-β (Aβ) degradation and improves memory function in an Alzheimer's disease model. Protein levels of two types of serine-phosphorylated insulin receptor substrate-1 (IRS-1), pS616 and pS636/639, significantly decreased following Apomorphine treatment in the 13-month-old 3xTg-AD mice brain, suggesting improved brain insulin resistance.
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盐酸去水吗啡名称

[ CAS 号 ]:
314-19-2

[ 中文名 ]:
R-(-)-阿朴吗啡盐酸盐

[ 英文名 ]:
A 922500

[中文别名 ]:

[英文别名 ]:

盐酸去水吗啡物理化学性质

[ 沸点 ]:
473.4ºC at 760mmHg

[ 熔点 ]:
195ºC (decomposes)

[ 分子式 ]:
C17H18ClNO2

[ 分子量 ]:
303.783

[ 闪点 ]:
268.8ºC

[ 精确质量 ]:
303.102600

[ PSA ]:
43.70000

[ LogP ]:
3.58980

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

盐酸去水吗啡毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HQ1750000
CHEMICAL NAME :
4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, (R)-
CAS REGISTRY NUMBER :
314-19-2
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C17-H17-N-O2.Cl-H
MOLECULAR WEIGHT :
303.81
WISWESSER LINE NOTATION :
T C6666 1A Q KN&TT&J DQ EQ K1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
145 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
38 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraarterial
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
20 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 137,17,1984
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盐酸去水吗啡安全信息

[ 危险品运输编码 ]:
UN 3249

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

盐酸去水吗啡合成路线

盐酸去水吗啡上下游产品

推荐生产厂家/供应商:

公司名:上海化源世纪贸易有限公司

区域:上海市普陀区

价格:

联系人:徐经理

产品详情:(R)-(-)-Apomorphine hydrochloride


公司名:上海源溪生物科技有限公司

区域:上海市浦东新区

价格:
¥需询单/1g

联系人:赖经理

产品详情:Apomorphine Hydrochloride


公司名:上海脉铂医药科技有限公司

区域:上海市嘉定区

价格:
¥759.0/1g ¥2361.0/100mg ¥1298.0/50mg ¥需询单/1g

联系人:李先生

产品详情:(R)-(-)-Apomorphine hydrochloride


公司名:上海创赛科技有限公司

区域:上海市嘉定区

价格:
¥需询单/1ml ¥2324.56/100mg ¥1282.82/50mg

联系人:夏言

产品详情:(R)-(-)-Apomorphine hydrochloride


公司名:上海阿拉丁生化科技股份有限公司

区域:上海市浦东新区

价格:
¥1070.0/50mg ¥需询单/1g ¥需询单/1g ¥需询单/1g

联系人:阿拉丁

产品详情:A 922500


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相关化合物

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标题:盐酸去水吗啡_用途_熔点_沸点_盐酸去水吗啡CAS号【314-19-2】_化源网 地址:https://m.chemsrc.com/mip/cas/314-19-2_1104950.html