4-[(4-methoxyphenyl)methylideneamino]-1,5-dimethyl-2-phenylpyrazol-3-one

名称

[ CAS 号 ]:
32061-14-6

[ 英文名 ]:
4-[(4-methoxyphenyl)methylideneamino]-1,5-dimethyl-2-phenylpyrazol-3-one

[英文别名 ]:

ANTIPYRINE,4-((p-METHOXYBENZYLIDENE)AMINO)
4-((p-Methoxybenzylidene)amino)antipyrine
IS 4
4-(Anisylideneamino)antipyrine
4-<(N-4-methoxybenzalidene)amino>antipyrine
4-Anisilidino-amino-antipyrine
4-Anisylidino-(aminoantipyrine)

物理化学性质

[ 密度 ]:
1.14g/cm3

[ 沸点 ]:
453.1ºC at 760 mmHg

[ 分子式 ]:
C₁₉H₁₉N₃O₂

[ 分子量 ]:
321.37300

[ 闪点 ]:
227.8ºC

[ 精确质量 ]:
321.14800

[ PSA ]:
48.52000

[ LogP ]:
3.24360

[ 折射率 ]:
1.593

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CD2995820

CHEMICAL NAME :: Antipyrine, 4-((p-methoxybenzylidene)amino)-

CAS REGISTRY NUMBER :: 32061-14-6

BEILSTEIN REFERENCE NO. :: 0308183

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C19-H19-N3-O2

MOLECULAR WEIGHT :: 321.41

WISWESSER LINE NOTATION :: T5NNVJ A1 BR& DNU1R DO1& E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 428 mg/kg/20D-I

TOXIC EFFECTS :: Behavioral - hallucinations, distorted perceptions

REFERENCE :: JDGRAX Journal of Drug Research. (National Organization for Drug Research and Control, POB 29, Cairo, Egypt) V.2- 1969- Volume(issue)/page/year: 15(1-2),103,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JDGRAX Journal of Drug Research. (National Organization for Drug Research and Control, POB 29, Cairo, Egypt) V.2- 1969- Volume(issue)/page/year: 9(1-2),183,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JDGRAX Journal of Drug Research. (National Organization for Drug Research and Control, POB 29, Cairo, Egypt) V.2- 1969- Volume(issue)/page/year: 4,89,1972

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安全信息

[ 海关编码 ]:
2933199090

合成路线

详细合成路线

海关

[ 海关编码 ]: 2933199090

[ 中文概述 ]:
2933199090. 其他结构上有非稠合吡唑环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%