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N -乙酰- D- 乳糖胺

N -乙酰- D- 乳糖胺用途

N-乙酰氨基乳糖(LacNAc)是一种含氮双糖,是糖蛋白和唾液酸Lewis X等多种低聚糖的重要组成部分。N-乙酰氨基乳糖可作为合成各种低聚糖的起始材料。N-乙酰氨基乳糖具有益生作用[1][2]。

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N -乙酰- D- 乳糖胺名称

[ CAS 号 ]:
32181-59-2

[ 中文名 ]:
N-乙酰-D-乳糖胺

[ 英文名 ]:
N-Acetyl-D-lactosamine

[中文别名 ]:

乙酰基乳糖胺

[英文别名 ]:

N-Acetyl-D-lactosamine
N-Acetyllactosamine
N-ACETYLLACTOSAMINE

N -乙酰- D- 乳糖胺生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Endo T, Koizumi S, Tabata K, Kakita S, Ozaki A. Large-scale production of N-acetyllactosamine through bacterial coupling. Carbohydr Res. 1999 Mar 31;316(1-4):179-83.

[2]. M.Karimi Alavijeh, et al. Simulation and economic assessment of large-scale enzymatic N-acetyllactosamine manufacture. Biochemical Engineering Journal. Volume 154, 15 February 2020, 107459

N -乙酰- D- 乳糖胺物理化学性质

[ 密度 ]:
1.64 g/cm3

[ 沸点 ]:
805.5ºC at 760 mmHg

[ 熔点 ]:
191-192ºC

[ 分子式 ]:
C₁₄H₂₅NO₁₁

[ 分子量 ]:
383.34800

[ 闪点 ]:
441ºC

[ 精确质量 ]:
383.14300

[ PSA ]:
198.40000

[ 外观性状 ]:
白色结晶固体

[ 折射率 ]:
1.623

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
H2O: 10 mg/mL, clear, colorless

N -乙酰- D- 乳糖胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-36/37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

N -乙酰- D- 乳糖胺合成路线

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N -乙酰- D- 乳糖胺文献

Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor.

J. Pharmacol. Exp. Ther. 353 , 505-16, (2015)

c-Jun N-terminal kinases (JNKs) participate in many physiologic and pathologic processes, including inflammatory diseases. We recently synthesized the sodium salt of IQ-1S (11H-indeno[1,2-b]quinoxalin...

BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival.

J. Exp. Med. 212 , 883-92, (2015)

B cell activating factor (BAFF) stimulation of the BAFF receptor (BAFF-R) is essential for the homeostatic survival of mature B cells. Earlier in vitro experiments with inhibitors that block MEK 1 and...

Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection.

J. Virol. 89 , 6918-27, (2015)

Human immunodeficiency virus (HIV) in humans and simian immunodeficiency virus (SIV) in macaques (MAC) lead to chronic inflammation and AIDS. Natural hosts, such as African green monkeys (AGM) and soo...

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