3Β-羟基-孕甾-16-烯-20-酮-3-醋酸酯

3Β-羟基-孕甾-16-烯-20-酮-3-醋酸酯名称

[ CAS 号 ]:
34675-77-9

[ 中文名 ]:
3Β-羟基-孕甾-16-烯-20-酮-3-醋酸酯

[ 英文名 ]:
Centpropazine

[中文别名 ]:

[英文别名 ]:

Centpropazine
Centropazine

3Β-羟基-孕甾-16-烯-20-酮-3-醋酸酯物理化学性质

[ 密度 ]:
1.147g/cm3

[ 沸点 ]:
560.7ºC at 760mmHg

[ 分子式 ]:
C₂₂H₂₈N₂O₃

[ 分子量 ]:
368.46900

[ 闪点 ]:
292.9ºC

[ 精确质量 ]:
368.21000

[ PSA ]:
53.01000

[ LogP ]:
2.84410

[ 折射率 ]:
1.576

3Β-羟基-孕甾-16-烯-20-酮-3-醋酸酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UC2984000

CHEMICAL NAME :: 1-Propanone, 1-(4-(2-hydroxy-3-(4-phenyl-1-piperazinyl)propoxy)phe nyl)-

CAS REGISTRY NUMBER :: 34675-77-9

BEILSTEIN REFERENCE NO. :: 0578135

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C22-H28-N2-O3

MOLECULAR WEIGHT :: 368.52

WISWESSER LINE NOTATION :: T6N DNTJ A1YQ1OR DV2& DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 1710 ug/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 5,338,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 270 mg/kg

TOXIC EFFECTS :: Behavioral - wakefulness

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,286,1972

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3Β-羟基-孕甾-16-烯-20-酮-3-醋酸酯安全信息

[ 海关编码 ]:
2933599090

3Β-羟基-孕甾-16-烯-20-酮-3-醋酸酯海关

[ 海关编码 ]: 2933599090

[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%