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齐洛呋胺

齐洛呋胺用途

Zylofuramine 是一种精神运动兴奋剂。

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齐洛呋胺名称

[ CAS 号 ]:
3563-92-6

[ 中文名 ]:
齐洛呋胺

[ 英文名 ]:
Zylofuramine

齐洛呋胺生物活性

[ 描述 ]:

Zylofuramine 是一种精神运动兴奋剂。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

[参考文献]

[1]. HARRIS LS, et al. ALPHA-BENZYLTETRAHYDROFURFURYLAMINES--A NEW SERIES OF PSYCHOMOTOR STIMULANTS. III. THE PHARMACOLOGY OF D-THREO ALPHA-BENZYL-N-ETHYLTETRAHYDROFURFURYLAMINE (ZYLOFURAMINE). Arch Int Pharmacodyn Ther. 1963 Dec 1;146:392-405.

齐洛呋胺物理化学性质

[ 密度 ]:
1.006g/cm3

[ 沸点 ]:
328.8ºC at 760mmHg

[ 分子式 ]:
C₁₄H₂₁NO

[ 分子量 ]:
219.32300

[ 闪点 ]:
137.2ºC

[ 精确质量 ]:
219.16200

[ PSA ]:
21.26000

[ LogP ]:
2.77710

[ 折射率 ]:
1.523

[ 储存条件 ]:
2-8℃

齐洛呋胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LU9400000

CHEMICAL NAME :: Furfurylamine, alpha-benzyl-N-ethyl-tetrahydro-, D-threo-

CAS REGISTRY NUMBER :: 3563-92-6

BEILSTEIN REFERENCE NO. :: 1371229

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C14-H21-N-O

MOLECULAR WEIGHT :: 219.36

WISWESSER LINE NOTATION :: T5OTJ BYM2&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 475 mg/kg

TOXIC EFFECTS :: Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 146,392,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 155 mg/kg

TOXIC EFFECTS :: Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 146,392,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 146,392,1963