卡非氨酯

卡非氨酯用途

苯乙炔基甲醇氨基甲酸酯是一种催眠剂[1]。

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卡非氨酯名称

[ CAS 号 ]:
3567-38-2

[ 中文名 ]:
卡非氨酯

[ 英文名 ]:
Phenylethynylcarbinol carbamate

[英文别名 ]:

Phenylethynylcarbinol carbamate
Carfimat
1-Phenyl-2-propynyl carbamate
Nirvotin
Carfimate

卡非氨酯生物活性

[ 描述 ]:

苯乙炔基甲醇氨基甲酸酯是一种催眠剂[1]。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

[参考文献]

[1]. GHISONI T. A proposito di un nuovo ipnotico, carbammato di fenil-etinil-carbinolo [A new hypnotic drug, phenylethynylcarbinol carbamate]. Gazz Med Ital. 1956;115(8):242-247.

卡非氨酯物理化学性质

[ 密度 ]:
1.192g/cm3

[ 沸点 ]:
320.2ºC at 760mmHg

[ 分子式 ]:
C₁₀H₉NO₂

[ 分子量 ]:
175.18400

[ 闪点 ]:
165.2ºC

[ 精确质量 ]:
175.06300

[ PSA ]:
53.31000

[ LogP ]:
1.97000

[ 折射率 ]:
1.569

卡非氨酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DO5950000

CHEMICAL NAME :: Benzyl alcohol, alpha-ethynyl-, carbamate

CAS REGISTRY NUMBER :: 3567-38-2

BEILSTEIN REFERENCE NO. :: 3200625

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H9-N-O2

MOLECULAR WEIGHT :: 175.20

WISWESSER LINE NOTATION :: ZVOYR&1UU1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 99,245,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 99,245,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 6,136,1956

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卡非氨酯安全信息

[ 海关编码 ]:
2924299090

卡非氨酯合成路线

详细合成路线

卡非氨酯海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%