17beta-Estradiol 3-tetrahydropyranyl ether

名称

[ CAS 号 ]:
3589-90-0

[ 英文名 ]:
17beta-Estradiol 3-tetrahydropyranyl ether

[英文别名 ]:

物理化学性质

[ 密度 ]:
1.16g/cm3

[ 沸点 ]:
508.8ºC at 760 mmHg

[ 分子式 ]:
C23H32O3

[ 分子量 ]:
356.49800

[ 闪点 ]:
261.5ºC

[ 精确质量 ]:
356.23500

[ PSA ]:
38.69000

[ LogP ]:
5.16010

[ 折射率 ]:
1.585

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KG7742000
CHEMICAL NAME :
Estra-1,3,5(10)-trien-3-ol, 17-beta-(tetrahydro-2H-pyran-2-yloxy)-
CAS REGISTRY NUMBER :
3589-90-0
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C23-H32-O3
MOLECULAR WEIGHT :
356.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
26400 ng/kg
SEX/DURATION :
female 3 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 20,211,1969
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
3 mg/kg
SEX/DURATION :
female 1-3 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
REFERENCE :
FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 20,211,1969
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
1500 ug/kg
SEX/DURATION :
female 1-3 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 20,211,1969
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