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肌苷-5'-三磷酸三钠盐

肌苷-5'-三磷酸三钠盐用途

Inosine-5'-triphosphate trisodium salt 是一种三磷酸核苷,可作为 ATPases 和 GTPases 的底物。

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肌苷-5'-三磷酸三钠盐名称

[ CAS 号 ]:
35908-31-7

[ 中文名 ]:
肌苷-5’-三磷酸三钠盐

[ 英文名 ]:
Inosine 5'-triphosphate (sodium salt)

[中文别名 ]:

[英文别名 ]:

Trisodium Inosine 5'-Triphosphate Hydrate
Inosine 5'-Triphosphate Trisodium Salt Hydrate
itp
INOSINE 5'-TRIPHOSPHATE SODIUM SALT
Inosine-5'-triphosphatetrisodiumsalt
ITP.Na3
Inosine 5'-triphosphate trisodium salt
INOSINE 5''-TRIPHOSPHATE SODIUM SALT HYDRATE
5'-ITP 3Na Hydrate
MFCD00084678

肌苷-5'-三磷酸三钠盐生物活性

[ 描述 ]:

Inosine-5'-triphosphate trisodium salt 是一种三磷酸核苷,可作为 ATPases 和 GTPases 的底物。

[参考文献]

[1]. Hanson RL, et al. Energy-transducing adenosine triphosphatase from Escherichia coli: purification, properties, and inhibition by antibody. J Bacteriol. 1973 May;114(2):772-81.

[2]. Pieper U, et al. The GTP-binding domain of McrB: more than just a variation on a common theme? J Mol Biol. 1999 Sep 24;292(3):547-56.

[3]. Klinker JF, et al. Functionally nonequivalent interactions of guanosine 5'-triphosphate, inosine 5'-triphosphate, and xanthosine 5'-triphosphate with the retinal G-protein, transducin, and with Gi-proteins in HL-60 leukemia cell membranes. Biochem Pharmacol. 1997 Sep 1;54(5):551-62.

[4]. Iuodka BA, et al. te specificity of T4 RNA-ligase: the role of a purine nucleotide base in forming a covalent AMP-RNA-ligase complex. Biokhimiia. 1993 Jun;58(6):857-65.

肌苷-5'-三磷酸三钠盐物理化学性质

[ 密度 ]:
2.63g/cm3

[ 沸点 ]:
994.9ºC at 760mmHg

[ 分子式 ]:
C₁₀H₁₂N₄Na₃O₁₄P₃

[ 分子量 ]:
574.111

[ 闪点 ]:
555.5ºC

[ 精确质量 ]:
573.925598

[ PSA ]:
311.26000

[ 外观性状 ]:
白色粉末

[ 储存条件 ]:
0-10°C;存放于惰性气体之中;避免湿气 (分解),加热

肌苷-5'-三磷酸三钠盐MSDS

详细MSDS(安全技术说明书)

肌苷-5'-三磷酸三钠盐安全信息

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1.0

肌苷-5'-三磷酸三钠盐文献

[Nucleoside-5'-triphosphate hydrolysis in the liver and kidney of rats with chronic alloxan diabetes].

Biomed. Khim. 52 , 364-369, (2006)

Activity and some properties of a soluble enzyme hydrolyzing nucleoside-5'-triphosphates were studied in the liver and kidney of normal and diabetic rats. The enzyme activity was shown to be reduced b...

Mapping interactions between the Ca2+-ATPase and its substrate ATP with infrared spectroscopy.

J. Biol. Chem. 278 , 10112-10118, (2003)

Infrared spectroscopy has been used to map substrate-protein interactions: the conformational changes of the sarcoplasmic reticulum Ca(2+)-ATPase upon nucleotide binding and ATPase phosphorylation wer...

Identification of an ITPase/XTPase in Escherichia coli by structural and biochemical analysis.

Structure 13 , 1511-1520, (2005)

Inosine triphosphate (ITP) and xanthosine triphosphate (XTP) are formed upon deamination of ATP and GTP as a result of exposure to chemical mutagens and oxidative damage. Nucleic acid synthesis requir...

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