beta-Piperidinoethyl benzhydryl ether hydrochloride

名称

[ CAS 号 ]:
3626-66-2

[ 英文名 ]:
beta-Piperidinoethyl benzhydryl ether hydrochloride

[英文别名 ]:

1-(2-Benzhydryloxy-aethyl)-piperidin
1-(2-benzhydryloxy-ethyl)-piperidine
<2-Piperidino-ethyl>-diphenylmethyl-ether
1-Piperidino-2-benzhydryloxy-ethan
1-(2-benzhydryloxy-ethyl)-piperidine,hydrochloride
Perastine
1-<2-Diphenylmethoxy-ethyl>-piperidin
1-(2-Benzhydryloxy-aethyl)-piperidin,Hydrochlorid
Perastinhydrochlorid
Perastine [INN]

物理化学性质

[ 沸点 ]:
407.5ºC at 760 mmHg

[ 分子式 ]:
C₂₀H₂₆ClNO

[ 分子量 ]:
331.88000

[ 闪点 ]:
176.8ºC

[ 精确质量 ]:
331.17000

[ PSA ]:
12.47000

[ LogP ]:
5.01840

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM7760000

CHEMICAL NAME :: Piperidine, 1-(2-(diphenylmethoxy)ethyl)-, hydrochloride

CAS REGISTRY NUMBER :: 3626-66-2

LAST UPDATED :: 199712

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H25-N-O.Cl-H

MOLECULAR WEIGHT :: 331.92

WISWESSER LINE NOTATION :: T6NTJ A2OYR&R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 102,250,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 97 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 5,709,1955

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 83,120,1945

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CCCCAK Collection of Czechoslovak Chemical Communications. (Academic Press Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK) V.1- 1929- Volume(issue)/page/year: 13,326,1948

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安全信息

[ 海关编码 ]:
2933399090

海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%