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4-氟-2-硝基苯胺

4-氟-2-硝基苯胺用途

【用途一】
用作医药中间体

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4-氟-2-硝基苯胺名称

[ CAS 号 ]:
364-78-3

[ 中文名 ]:
4-氟-2-硝基苯胺

[ 英文名 ]:
4-Fluoro-2-nitroaniline

[中文别名 ]:

[英文别名 ]:

MFCD00007830
4-Fluoro-2-nitroaniline
Benzenamine, 4-fluoro-2-nitro-
4-Fluoro-2-nitrobenzeneamine
4-fluoro-2-nitrobenzenamine
EINECS 206-666-0

4-氟-2-硝基苯胺物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
295.1±20.0 °C at 760 mmHg

[ 熔点 ]:
90-94 °C(lit.)

[ 分子式 ]:
C₆H₅FN₂O₂

[ 分子量 ]:
156.115

[ 闪点 ]:
89.4±0.0 °C

[ 精确质量 ]:
156.033508

[ PSA ]:
71.84000

[ LogP ]:
1.94

[ 外观性状 ]:
淡黄色晶体

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.603

[ 储存条件 ]:
室温

[ 水溶解性 ]:
INSOLUBLE

4-氟-2-硝基苯胺MSDS

4-氟-2-硝基苯胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302 + H312 + H332-H315-H319-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36/37-S36/37/39

[ 危险品运输编码 ]:
2811

[ WGK德国 ]:
3

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2921420090

4-氟-2-硝基苯胺合成路线

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4-氟-2-硝基苯胺上游产品

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4-氟-2-硝基苯胺海关

[ 海关编码 ]: 2921420090

[ 中文概述 ]:
2921420090 其他苯胺衍生物及其盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

4-氟-2-硝基苯胺文献

Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease.

J. Pharmacol. Exp. Ther. 296 , 600-611, (2001)

The diseases of cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are characterized by mucus-congested airways. Agents that stimulate the secretion of Cl- are anticipated to facili...

Clozapine derived 2,3-dihydro-1H-1,4- and 1,5-benzodiazepines with D4 receptor selectivity: synthesis and biological testing.

Bioorg. Med. Chem. 12(10) , 2625-37, (2004)

Novel 4-arylpiperazin-1-yl-substituted 2,3-dihydro-1H-1,4- and 1H-1,5-benzodiazepines and their aza-analogues were synthesized as debenzoclozapine derivatives for evaluation as potential D4-ligands. W...

Complexes of copper (II), nickel (II) and cobalt (II) with 2-fluoro, 5-nitroaniline and 4-fluoro, 2-nitroaniline. DeVoto G, et al.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 38(7) , 725-728, (1982)

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