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3-氯-4-氟苯胺

3-氯-4-氟苯胺用途

4-氟-3-氯苯胺是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

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3-氯-4-氟苯胺名称

[ CAS 号 ]:
367-21-5

[ 中文名 ]:
3-氯-4-氟苯胺

[ 英文名 ]:
3-Chloro-4-fluoroaniline

[中文别名 ]:

[英文别名 ]:

3-Chloro-4-fluoroaniline
para-fluoro-meta-chloroaniline
Benzenamine, 3-chloro-4-fluoro-
3-chlor-4-fluoranilin
3-Chloro-4-fluorobenzenamine
3-Cl-4-F-aniline
4-fluoro-3-chloro-aniline
Benzenamine,3-chloro-4-fluoro
3-Chloro-4-fluorophenylamine
Aniline,3-chloro-4-fluoro

3-氯-4-氟苯胺生物活性

[ 描述 ]:

4-氟-3-氯苯胺是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

[体外研究]

吉非替尼杂质五、是一种有机氟化结构单元,用于合成药物和生物活性化合物。它具有抗炎活性。

3-氯-4-氟苯胺物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
227.5±0.0 °C at 760 mmHg

[ 熔点 ]:
42-44 °C(lit.)

[ 分子式 ]:
C₆H₅ClFN

[ 分子量 ]:
145.56

[ 闪点 ]:
99.4±21.8 °C

[ 精确质量 ]:
145.009460

[ PSA ]:
26.02000

[ LogP ]:
2.14

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C

[ 折射率 ]:
1.570

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, chloroformates. May be air-sensitive.

[ 水溶解性 ]:
10 g/L (20 ºC)

3-氯-4-氟苯胺MSDS

3-氯-4-氟苯胺安全信息

[ 符号 ]:

GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301 + H311 + H331-H373

[ 警示性声明 ]:
P261-P280-P301 + P310-P311

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T:Toxic

[ 风险声明 (欧洲) ]:
R23/24/25;R33

[ 安全声明 (欧洲) ]:
S36/37/39-S45-S26

[ 危险品运输编码 ]:
UN 2811 6.1/PG 2

[ WGK德国 ]:
2

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
29214210

3-氯-4-氟苯胺合成路线

3-氯-4-氟苯胺上下游产品

3-氯-4-氟苯胺上游产品

3-氯-4-氟苯胺下游产品

3-氯-4-氟苯胺制备

以邻二氯苯为原料，经硝酸硝化、氢气还原而得。

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3-氯-4-氟苯胺海关

[ 海关编码 ]: 2921420090

[ 中文概述 ]:
2921420090 其他苯胺衍生物及其盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

3-氯-4-氟苯胺文献

Reductive deamination as a new step in the anaerobic microbial degradation of halogenated anilines.

FEMS Microbiol. Lett. 209(2) , 307-12, (2002)

In this paper we report the isolation and characterization of an anaerobic enrichment culture as well as of a Rhodococcus sp. strain 2 capable of degrading 3,4-dihaloanilines under nitrate reducing co...

An improved analytical method, based on HPLC with electrochemical detection, for monitoring exposure to 3-chloro-4-fluoroaniline.

J. Anal. Toxicol. 12(6) , 330-3, (1988)

An HPLC method for monitoring exposure of workers to 3-chloro-4-fluoroaniline (CFA) is described. It is based on the detection of a major urinary metabolite, 2-amino-4-chloro-5-fluorophenyl sulphate, ...

Biological monitoring of exposure to 3-chloro-4-fluoroaniline by determination of a urinary metabolite and a hemoglobin adduct.

Environ. Health Perspect. 102 Suppl 6 , 23-5, (1994)

In two studies, involving 75 and 72 workers, potential exposure to 3-chloro-4-fluoroaniline (CFA) was biologically monitored by determination of its main urinary metabolite 2-amino-4-chloro-5-fluoroph...

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