(-)-p-Chloroamphetamine hydrochloride

(-)-p-Chloroamphetamine hydrochloride名称

[ CAS 号 ]:
3706-38-5

[ 英文名 ]:
(-)-p-Chloroamphetamine hydrochloride

[英文别名 ]:

para-chloroamphetamine HCl
(+)-p-Chloro-α-methylphenethylamine hydrochloride
4-chloroamphetamine hydrochloride
p-Chloroamphetamine hydrochloride
(-)-p-Chloro-α-methylphenethylamine hydrochloride
(-)-p-Chloroamphetamine hydrochloride
(+)-p-chloroamphetamine hydrochloride
DL-P-CHLOROAMPHETAMINE HCL

(-)-p-Chloroamphetamine hydrochloride物理化学性质

[ 沸点 ]:
244.2ºC at 760mmHg

[ 熔点 ]:
168-170ºC(lit.)

[ 分子式 ]:
C₉H₁₃Cl₂N

[ 分子量 ]:
206.112

[ 闪点 ]:
117ºC

[ 精确质量 ]:
205.042511

[ PSA ]:
26.02000

[ LogP ]:
3.73200

(-)-p-Chloroamphetamine hydrochlorideMSDS

详细MSDS(安全技术说明书)

(-)-p-Chloroamphetamine hydrochloride毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SH1925000

CHEMICAL NAME :: Phenethylamine, p-chloro-alpha-methyl-, hydrochloride, (+-)-

CAS REGISTRY NUMBER :: 3706-38-5

LAST UPDATED :: 199012

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H12-Cl-N.Cl-H

MOLECULAR WEIGHT :: 206.13

WISWESSER LINE NOTATION :: Z1Y1&R DG &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) Vascular - BP elevation not characterized in autonomic section

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,100,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12 mg/kg

TOXIC EFFECTS :: Behavioral - excitement Behavioral - changes in motor activity (specific assay)

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 170,428,1967 *** REVIEWS *** TOXICOLOGY REVIEW 17XKAB "International Symposium on Amphetamines and Related Compounds, Proceedings, Mario Negri Institute for Pharmacological Research, Milan, 1969," Costa, E., and S. Garattini, eds., New York, Raven Press, 1970 Volume(issue)/page/year: -,343,1970

点击显示

(-)-p-Chloroamphetamine hydrochloride安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301

[ 警示性声明 ]:
P301 + P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T: Toxic;

[ 风险声明 (欧洲) ]:
25

[ 安全声明 (欧洲) ]:
45

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII

[ RTECS号 ]:
SH1925000

[ 海关编码 ]:
2921499090

(-)-p-Chloroamphetamine hydrochloride海关

[ 海关编码 ]: 2921499090

[ 中文概述 ]:
2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

(-)-p-Chloroamphetamine hydrochloride文献

Pyrrolidone carboxylic acid levels or caspase-14 expression in the corneocytes of lesional skin correlates with clinical severity, skin barrier function and lesional inflammation in atopic dermatitis.

J. Dermatol. Sci. 76(3) , 231-9, (2014)

Dry skin in atopic dermatitis (AD) mainly results from barrier impairment due to deficiency of ceramide and natural moisturizing factors including pyrrolidone carboxylic acid (PCA) in stratum corneum ...

Metabolic imaging of pancreatic ductal adenocarcinoma detects altered choline metabolism.

Clin. Cancer Res. 21(2) , 386-95, (2015)

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal disease that develops relatively symptom-free and is therefore advanced at the time of diagnosis. The absence of early symptoms and ...

Organic amendments to avocado crops induce suppressiveness and influence the composition and activity of soil microbial communities.

Appl. Environ. Microbiol. 81(10) , 3405-18, (2015)

One of the main avocado diseases in southern Spain is white root rot caused by the fungus Rosellinia necatrix Prill. The use of organic soil amendments to enhance the suppressiveness of natural soil i...

更多文献