alpha-1,3-Galactosyltransferase(GTB)

alpha-1,3-Galactosyltransferase(GTB)用途

α-1,3-半乳糖基转移酶(GTB)(α3GT)催化异种抗原或α-半乳糖(α-Gal)表位的合成。α-1,3-半乳糖基转移酶(GTB)将半乳糖从UDP-Gal转移到1型或2型,αFuc1→2βGal-R(H)-终止受体[1]。

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alpha-1,3-Galactosyltransferase(GTB)名称

[ CAS 号 ]:
37257-33-3

[ 英文名 ]:
alpha-1,3-Galactosyltransferase(GTB)

alpha-1,3-Galactosyltransferase(GTB)生物活性

[ 描述 ]:

α-1,3-半乳糖基转移酶(GTB)(α3GT)催化异种抗原或α-半乳糖(α-Gal)表位的合成。α-1,3-半乳糖基转移酶(GTB)将半乳糖从UDP-Gal转移到1型或2型,αFuc1→2βGal-R(H)-终止受体[1]。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Sandra L Marcus, et al. A single point mutation reverses the donor specificity of human blood group B-synthesizing galactosyltransferase. J Biol Chem. 2003 Apr 4;278(14):12403-5.

[2]. Nethaji Thiyagarajan, et al. Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen. Sci Rep. 2012;2:940.

alpha-1,3-Galactosyltransferase(GTB)物理化学性质

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