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4-硝基苯-Α-D-葡吡喃糖苷

4-硝基苯-Α-D-葡吡喃糖苷用途

4-硝基苯基a-D-吡喃葡萄糖苷是α-葡萄糖苷酶的显色底物。4-硝基苯基a-D-吡喃葡萄糖苷可用于测量α-葡萄糖苷酶活性[1][2]。

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4-硝基苯-Α-D-葡吡喃糖苷名称

[ CAS 号 ]:
3767-28-0

[ 中文名 ]:
对硝基苯-α-D-葡萄糖吡喃苷

[ 英文名 ]:
4-nitrophenyl α-D-glucoside

[中文别名 ]:

[英文别名 ]:

4-Nitrophenyl α-D-glucopyranoside
4-Nitrophenyl α-D-Glucopyranoside [Substrate
MFCD00064088
4-nitrophenyl α-D-glucoside
EINECS 223-189-3
α-D-Glucopyranoside, 4-nitrophenyl
4-Nitrophenyl a-D-glucopyranoside

4-硝基苯-Α-D-葡吡喃糖苷生物活性

[ 描述 ]:

4-硝基苯基a-D-吡喃葡萄糖苷是α-葡萄糖苷酶的显色底物。4-硝基苯基a-D-吡喃葡萄糖苷可用于测量α-葡萄糖苷酶活性[1][2]。

[ 相关类别 ]:

研究领域 >> 其他

[体外研究]

4-硝基苯基a-D-吡喃葡萄糖苷通过酶促裂解释放对硝基苯酚。4-硝基苯基a-D-吡喃葡萄糖苷可以通过 405纳米的比色检测进行定量[2]。

[参考文献]

[1]. Zeng L, et, al. Inhibitory mechanism of morin on α-glucosidase and its anti-glycation properties. Food Funct. 2016 Sep 14;7(9):3953-63.

[2]. Binder TP, et, al. p-Nitrophenyl alpha-D-glucopyranoside, a new substrate for glucansucrases. Carbohydr Res. 1983 Dec 23;124(2):287-99.

4-硝基苯-Α-D-葡吡喃糖苷物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
582.2±50.0 °C at 760 mmHg

[ 熔点 ]:
210-216ºC

[ 分子式 ]:
C₁₂H₁₅NO₈

[ 分子量 ]:
301.249

[ 闪点 ]:
305.9±30.1 °C

[ 精确质量 ]:
301.079773

[ PSA ]:
145.20000

[ LogP ]:
-0.55

[ 外观性状 ]:
白色至灰白色粉末

[ 蒸汽压 ]:
0.0±1.7 mmHg at 25°C

[ 折射率 ]:
1.648

[ 储存条件 ]:
2-8°C

4-硝基苯-Α-D-葡吡喃糖苷MSDS

4-硝基苯-Α-D-葡吡喃糖苷安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

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4-硝基苯-Α-D-葡吡喃糖苷文献

Pregnane-type steroidal glycosides from Gymnema griffithii Craib.

Phytochemistry 106 , 197-206, (2014)

Eight pregnane-type steroidal glycosides substituted with ortho-acetate groups were isolated from the methanolic extract of the pericarp of Gymnema griffithii fruits, and named gymnemogriffithosides A...

Alpha-amylase Inhibition and Antioxidant Activity of Marine Green Algae and its Possible Role in Diabetes Management.

Pharmacogn. Mag. 11 , S511-5, (2016)

In the continuing search for safe and efficient antidiabetic drug, marine algae become important source which provide several compounds of immense therapeutic potential. Alpha-amylase, alpha-glucosida...

Selective α-glucosidase substrates and inhibitors containing short aromatic peptidyl moieties.

Bioorg. Med. Chem. Lett. 21 , 2441-4, (2011)

We constructed a library of sugar-dipeptide conjugate to find out the best complementary against hydrophobic pocket of α-glucosidase. The best substrate showed 150-fold improved K(m) value relative p-...

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