N,N-DIMETHYL-10-(3-(4-(METHYLSULFONYL)-1-PIPERAZINYL)PROPYL) PHENOTHIAZINE-2-SULFONAMIDE
名称
[ CAS 号 ]:
3773-37-3
[ 英文名 ]:
N,N-DIMETHYL-10-(3-(4-(METHYLSULFONYL)-1-PIPERAZINYL)PROPYL) PHENOTHIAZINE-2-SULFONAMIDE
[英文别名 ]:
- 9260 rp
- rp 9260
物理化学性质
[ 密度 ]:
1.45g/cm3
[ 沸点 ]:
687.3ºC at 760 mmHg
[ 分子式 ]:
C22H30N4O4S3
[ 分子量 ]:
510.69300
[ 闪点 ]:
369.5ºC
[ 精确质量 ]:
510.14300
[ PSA ]:
123.30000
[ LogP ]:
4.60930
[ 折射率 ]:
1.692
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SP5600000
- CHEMICAL NAME :
- Phenothiazine-2-sulfonamide, N,N-dimethyl-10-(3-(4-(methylsulfonyl)-1-piperazinyl) propyl)-
- CAS REGISTRY NUMBER :
- 3773-37-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C22-H30-N4-O4-S3
- MOLECULAR WEIGHT :
- 510.74
- WISWESSER LINE NOTATION :
- T C666 BN ISJ ESWN1&1 B3- AT6N DNTJ DSW1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 2 mg/kg
- TOXIC EFFECTS :
- Behavioral - sleep Behavioral - excitement Gastrointestinal - nausea or vomiting
- REFERENCE :
- PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 2,209,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 2,209,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 480 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 2,209,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 2,209,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 310 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 2,209,1961
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相关化合物
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