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GM1 神经节苷脂钠盐,来源于猪脑

GM1 神经节苷脂钠盐,来源于猪脑用途

Ganglioside GM1 是神经节苷脂家族的成员,可用于神经系统疾病研究。Ganglioside GM1 是霍乱毒素 1 的功能性组织受体。

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GM1 神经节苷脂钠盐,来源于猪脑名称

[ CAS 号 ]:
37758-47-7

[ 中文名 ]:
单唾液神经节苷酯

[ 英文名 ]:
Ganglioside GM1

[中文别名 ]:

单唾液酸神经节苷酯

[英文别名 ]:

GM1 Ganglioside,Brain,Ovine-Sodium Salt)
Ganglioside GM1,monosialo
GANGLIOSIDE GM1, AMMONIUM SALT, BOVINE
MFCD00466936

GM1 神经节苷脂钠盐,来源于猪脑生物活性

[ 描述 ]:

Ganglioside GM1 是神经节苷脂家族的成员,可用于神经系统疾病研究。Ganglioside GM1 是霍乱毒素 1 的功能性组织受体。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

[参考文献]

[1]. Wenchao Zhang, et al. Pathophysiology of Ganglioside GM1 in Ischemic Stroke: Ganglioside GM1: A Critical Review. Cell Transplant. 2019 Jun;28(6):657-661.

GM1 神经节苷脂钠盐,来源于猪脑物理化学性质

[ 密度 ]:
1.35 g/cm3

[ 沸点 ]:
1527ºC at 760 mmHg

[ 熔点 ]:
207-230ºC

[ 分子式 ]:
C₇₇H₁₃₉N₃O₃₁

[ 分子量 ]:
1602.93000

[ 闪点 ]:
877.3ºC

[ 精确质量 ]:
1601.94000

[ PSA ]:
540.58000

[ LogP ]:
1.69070

[ 外观性状 ]:
冻干的粉末

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
chloroform/methanol (9:1): 10 mg/mL, clear, colorless

GM1 神经节苷脂钠盐,来源于猪脑MSDS

详细MSDS(安全技术说明书)

GM1 神经节苷脂钠盐,来源于猪脑安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
FK1200000

[ 海关编码 ]:
29400090

GM1 神经节苷脂钠盐,来源于猪脑文献

Methylmercury causes neuronal cell death through the suppression of the TrkA pathway: in vitro and in vivo effects of TrkA pathway activators.

Toxicol. Appl. Pharmacol. 282(3) , 259-66, (2015)

Methylmercury (MeHg) is an environmental toxin which induces cell death specific for the nervous systems. Here we show that MeHg causes neuronal cell death through the suppression of the tropomyosin r...

Ganglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain.

J. Biol. Chem. 288(36) , 25804-9, (2013)

Cholera toxin causes diarrheal disease by binding ganglioside GM1 on the apical membrane of polarized intestinal epithelial cells and trafficking retrograde through sorting endosomes, the trans-Golgi ...

Fuzheng Huayu inhibits carbon tetrachloride-induced liver fibrosis in mice through activating hepatic NK cells.

J. Ethnopharmacol. 145(1) , 175-81, (2013)

Fuzheng Huayu (FZHY) is a Chinese compound herbal preparation which consists of six Chinese herbs. This study examines the preventative effects of FZHY on liver fibrosis induced by carbon tetrachlorid...

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