地芬诺酯盐酸盐
地芬诺酯盐酸盐用途
用于急、慢性功能性腹泻及慢性肠炎等 包 装: 25KG/DRUM
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地芬诺酯盐酸盐名称
[ CAS 号 ]:
3810-80-8
[ 中文名 ]:
地芬诺酯盐酸盐
[ 英文名 ]:
diphenoxylate hydrochloride
[中文别名 ]:
[英文别名 ]:
- DIPHENOXYLATE HYDROCHLORIDE
- DIPHENOXYLATE HYDROCHLORIDE ANTIPERISTAL TIC,ANTI
- DIPHENOXYLATE HCL
- r1132
地芬诺酯盐酸盐物理化学性质
[ 沸点 ]:
602.3ºC at 760mmHg
[ 熔点 ]:
220.0-222.5ºC
[ 分子式 ]:
C30H33ClN2O2
[ 分子量 ]:
489.048
[ 闪点 ]:
318ºC
[ 精确质量 ]:
488.223053
[ PSA ]:
53.33000
[ LogP ]:
6.22318
[ 储存条件 ]:
库房低温,通风,干燥,与食品原料分开存放
[ 水溶解性 ]:
Very slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in ethanol (96 per cent).
地芬诺酯盐酸盐毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NS5300000
- CHEMICAL NAME :
- Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride
- CAS REGISTRY NUMBER :
- 3810-80-8
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C30-H32-N2-O2.Cl-H
- MOLECULAR WEIGHT :
- 489.10
- WISWESSER LINE NOTATION :
- T6NTJ A2XR&R&CN DVO2 DR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 221 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1633,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1636,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >160 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1636,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3182 No. of Facilities: 105 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 8242 (estimated) No. of Female Employees: 7235 (estimated)
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地芬诺酯盐酸盐安全信息
[ 危险品运输编码 ]:
UN 1544
[ 包装等级 ]:
III
[ 危险类别 ]:
6.1(b)
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