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法可林

法可林用途

Azapentacene sodium 是一种抗白内障剂。

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法可林名称

[ CAS 号 ]:
3863-80-7

[ 中文名 ]:
法可林

[ 英文名 ]:
phacolysin

[中文别名 ]:

[英文别名 ]:

phacolysin
MFCD08458873
Azapentacene
Phacolin

法可林生物活性

[ 描述 ]:

Azapentacene sodium 是一种抗白内障剂。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[参考文献]

[1]. Shvachko AG, et al. [Chemiluminescence decrease of singlet oxygen in NaClO+H2O2 reaction in the presence of different anti-cataract drugs]. Biull Eksp Biol Med. 1991 Jul;112(7):42-4. Russian.

法可林物理化学性质

[ 分子式 ]:
C₁₈H₁₀N₄Na₂O₆S₂

[ 分子量 ]:
488.405

[ 精确质量 ]:
487.983704

[ PSA ]:
188.52000

[ LogP ]:
4.27760

法可林毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VD3655000

CAS REGISTRY NUMBER :: 3863-80-7

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C18-H12-N4.2O3-S.2Na

MOLECULAR WEIGHT :: 458.38

WISWESSER LINE NOTATION :: T G6 E6 C666 BM FN MM QNJ &.NA..S-O3 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,328,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,328,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1190 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,328,1982