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(LEU15)-GASTRIN I (HUMAN)

(LEU15)-GASTRIN I (HUMAN)用途

[Leu15]-胃泌素I(人)是一种肽。胃泌素通过称为胆囊收缩素(CCK)或CCK-B受体(CCK-BR)的G蛋白偶联受体发挥其功能[1]。

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(LEU15)-GASTRIN I (HUMAN)名称

[ CAS 号 ]:
39024-57-2

[ 中文名 ]:
(LEU15)-GASTRIN I (HUMAN)

[ 英文名 ]:
(Leu15)-Gastrin I (human)

[英文别名 ]:

[Leu15]-Gastrin I (human)

(LEU15)-GASTRIN I (HUMAN)生物活性

[ 描述 ]:

[Leu15]-胃泌素I(人)是一种肽。胃泌素通过称为胆囊收缩素(CCK)或CCK-B受体(CCK-BR)的G蛋白偶联受体发挥其功能[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Kleomenis Barlos, et al. Veresterung von partiell geschützten peptid-fragmenten mit harzen. Einsatz von 2-chlortritylchlorid zur synthese von Leu15 -gastrin I[J]. Tetrahedron Letters, 1989.

(LEU15)-GASTRIN I (HUMAN)物理化学性质

[ 分子式 ]:
C₉₈H₁₂₆N₂₀O₃₁

[ 分子量 ]:
2080.16000

[ 精确质量 ]:
2078.89000

[ PSA ]:
804.61000

[ LogP ]:
3.65640

(LEU15)-GASTRIN I (HUMAN)安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

(LEU15)-GASTRIN I (HUMAN)合成路线

详细合成路线

(LEU15)-GASTRIN I (HUMAN)文献

[Syntheses of human little gastrin-I and its leucine-15, norleucine-15 and methoxinine-15 analogs].

Hoppe. Seylers. Z. Physiol. Chem. 364 , 157, (1983)

Human little gastrin-I is known to exhibit a high tendency to air-oxidation of its methionine-15 residue to the corresponding S-oxide derivative, with concomitant loss of biological activity. Since it...

Cholecystokinin(CCK)-A and CCK-B/gastrin receptors in human tumors.

Cancer Res. 57 , 1377, (1997)

Cholecystokinin (CCK)-A and CCK-B/gastrin receptors were evaluated with in vitro receptor autoradiography in 406 human tumors of various origins using a sulfated 125I-labeled CCK decapeptide analogue ...

Gastrin does not stimulate growth of the rat pancreas.

Scand. J. Gastroenterol. 31 , 404-410, (1996)

Gastrin is thought to stimulate growth of the pancreas via gastrin/cholecystokinin (CCK)-B-type receptors. The aim of the present study was to examine the trophic response of the pancreas to exogenous...

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