弹性蛋白酶,来源猪胰腺

弹性蛋白酶,来源猪胰腺用途

Elastase from porcine pancreas 是具有 240 个氨基酸残基的单条多肽链。Elastase from porcine pancreas 是一种丝氨酸蛋白酶,可以水解蛋白质和多肽。Elastase from porcine pancreas 可诱发仓鼠气肿。

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弹性蛋白酶,来源猪胰腺名称

[ CAS 号 ]:
39445-21-1

[ 中文名 ]:
弹性蛋白酶

[ 英文名 ]:
Elastase from porcine pancreas

[英文别名 ]:

MFCD00130998
EINECS 254-453-6

弹性蛋白酶,来源猪胰腺生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[体内研究]

来自猪胰腺的弹性蛋白酶诱导仓鼠肺气肿[3]。

[参考文献]

[1]. Shotton DM, et, al. Amino-acid sequence of porcine pancreatic elastase and its homologies with other serine proteinases. Nature. 1970 Feb 28;225(5235):802-6.

[2]. Teshima T, et, al. A new class of heterocyclic serine protease inhibitors. Inhibition of human leukocyte elastase, porcine pancreatic elastase, cathepsin G, and bovine chymotrypsin A alpha with substituted benzoxazinones, quinazolines, and anthranilates. J Biol Chem. 1982 May 10;257(9):5085-91.

[3]. Stone PJ, et, al. Induction and exacerbation of emphysema in hamsters with human neutrophil elastase inactivated reversibly by a peptide boronic acid. Am Rev Respir Dis. 1990 Jan;141(1):47-52.

弹性蛋白酶,来源猪胰腺物理化学性质

[ 分子式 ]:
C₂₀H₃₁N₄O₇Cl

[ 分子量 ]:
474.93574

[ 外观性状 ]:
白色至黄色至米色粉末

[ 储存条件 ]:
-20°C

弹性蛋白酶,来源猪胰腺安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger, Warning

[ 危害声明 ]:
H315-H319-H334-H335

[ 警示性声明 ]:
P261-P280-P284-P304 + P340 + P312-P305 + P351 + P338-P337 + P313-P342 + P311

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R42;R36/37/38

[ 安全声明 (欧洲) ]:
S22;S24;S26;S36/S37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

弹性蛋白酶,来源猪胰腺制备

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弹性蛋白酶,来源猪胰腺文献

Targeting latent TGFβ release in muscular dystrophy.

Sci. Transl. Med. 6(259) , 259ra144, (2014)

Latent transforming growth factor-β (TGFβ) binding proteins (LTBPs) bind to inactive TGFβ in the extracellular matrix. In mice, muscular dystrophy symptoms are intensified by a genetic polymorphism th...

Can we predict postoperative pancreatic leakage after pancreaticoduodenectomy using preoperative fecal elastase-1 level?

J. Clin. Lab Anal. 27(5) , 379-83, (2013)

The measurement of fecal elastas-1 in stools is a sensitive and relatively inexpensive noninvasive test. The aim of this study was to study fecal elastase levels in patients who develop pancreatic lea...

Collagenase mRNA Overexpression and Decreased Extracellular Matrix Components Are Early Events in the Pathogenesis of Emphysema.

PLoS ONE 10 , e0129590, (2015)

To describe the progression of parenchymal remodeling and metalloproteinases gene expression in earlier stages of emphysema, mice received porcine pancreatic elastase (PPE) instillation and Control gr...

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弹性蛋白酶,来源猪胰腺

弹性蛋白酶,来源猪胰腺用途

弹性蛋白酶,来源猪胰腺名称

弹性蛋白酶,来源猪胰腺生物活性

弹性蛋白酶,来源猪胰腺物理化学性质

弹性蛋白酶,来源猪胰腺安全信息

弹性蛋白酶,来源猪胰腺制备

弹性蛋白酶,来源猪胰腺文献

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