4,5α-Epoxy-3-methoxy-17-methylmorphinan
名称
[ CAS 号 ]:
3990-01-0
[ 英文名 ]:
4,5α-Epoxy-3-methoxy-17-methylmorphinan
[英文别名 ]:
- (5α)-3-Methoxy-17-methyl-4,5-epoxymorphi
物理化学性质
[ 密度 ]:
1.23g/cm3
[ 沸点 ]:
416.2ºC at 760 mmHg
[ 分子式 ]:
C18H23NO2
[ 分子量 ]:
285.38100
[ 闪点 ]:
150.1ºC
[ 精确质量 ]:
285.17300
[ PSA ]:
21.70000
[ LogP ]:
2.69220
[ 折射率 ]:
1.621
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QC9000000
- CHEMICAL NAME :
- Morphinan, 4,5-alpha-epoxy-3-methoxy-17-methyl-
- CAS REGISTRY NUMBER :
- 3990-01-0
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H23-N-O2
- MOLECULAR WEIGHT :
- 285.42
- WISWESSER LINE NOTATION :
- T B6566 B6/CO 4ABBC R BX HO PN GHT&&TTJ JO1 P1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 131 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 55,257,1935
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