Rifamycin,3-[(4-methyl-1-piperidinyl)methyl]- (9CI)

名称

[ CAS 号 ]:
4075-47-2

[ 英文名 ]:
Rifamycin,3-[(4-methyl-1-piperidinyl)methyl]- (9CI)

物理化学性质

[ 密度 ]:
1.31g/cm3

[ 沸点 ]:
901.9ºC at 760 mmHg

[ 分子式 ]:
C44H60N2O12

[ 分子量 ]:
808.95300

[ 闪点 ]:
499.3ºC

[ 精确质量 ]:
808.41500

[ PSA ]:
204.55000

[ LogP ]:
6.06190

[ 折射率 ]:
1.626

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KD1920650
CHEMICAL NAME :
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy -8-(4-methylpiperidin omethyl)-, 21-acetate
CAS REGISTRY NUMBER :
4075-47-2
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C44-H60-N2-O12
MOLECULAR WEIGHT :
809.06

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
680 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 12,155,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
188 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 12,155,1967
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