帽柱木碱盐酸盐

帽柱木碱盐酸盐用途

Mitragynine is an indole alkaloid from the plant Mitragyna speciosa. It has stimulatory, antinociceptive, and opiate-like effects, acting through noradrenergic, serotonergic, and opioid receptors.1,2 Mitragynine has a higher affinity for the μ-opioid rece

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帽柱木碱盐酸盐名称

[ CAS 号 ]:
4098-40-2

[ 中文名 ]:
帽柱木碱盐酸盐

[ 英文名 ]:
Mitragynine

[中文别名 ]:

帽柱木碱

[英文别名 ]:

9-Methoxycorynantheidine
mitragynine picrate
Mitragynine
Mitragynine Crystal

帽柱木碱盐酸盐物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
560.3±50.0 °C at 760 mmHg

[ 熔点 ]:
92-95ºC

[ 分子式 ]:
C₂₉H₃₃N₅O₁₁

[ 分子量 ]:
398.495

[ 闪点 ]:
292.7±30.1 °C

[ 精确质量 ]:
398.220551

[ PSA ]:
221.48000

[ LogP ]:
3.88

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.605

帽柱木碱盐酸盐安全信息

[ 符号 ]:

GHS02, GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H301 + H311 + H331-H370

[ 警示性声明 ]:
P210-P260-P280-P301 + P310-P311

[ 危害码 (欧洲) ]:
F,T

[ 风险声明 (欧洲) ]:
11-23/24/25-39/23/24/25-36/37/38-22

[ 安全声明 (欧洲) ]:
7-16-36/37-45-26

[ 危险品运输编码 ]:
UN1230 - class 3 - PG 2 - Methanol, solution

[ 海关编码 ]:
29339900

帽柱木碱盐酸盐合成路线

详细合成路线

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帽柱木碱盐酸盐文献

A drug fatality involving Kratom.

J. Forensic Sci. 58 Suppl 1 , S278-9, (2013)

A 17-year-old white man who showed no obvious signs of trauma was found unresponsive in bed and was pronounced dead at the scene. The decedent had a documented history of heroin abuse and chronic back...

Orally active opioid compounds from a non-poppy source.

J. Med. Chem. 56(12) , 4840-8, (2013)

The basic science and clinical use of morphine and other "opioid" drugs are based almost exclusively on the extracts or analogues of compounds isolated from a single source, the opium poppy (Papaver s...

Determination of mitragynine in plasma with solid-phase extraction and rapid HPLC-UV analysis, and its application to a pharmacokinetic study in rat.

Anal. Bioanal. Chem 397(5) , 2023-30, (2010)

A new solid phase extraction method for rapid high performance liquid chromatography-UV determination of mitragynine in plasma has been developed. Optimal separation was achieved with an isocratic mob...

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