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巴豆醛

巴豆醛用途

【用途一】
丁烯-2-醛即巴豆醛是除草剂稀禾啶的中间体。
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巴豆醛名称

[ CAS 号 ]:
4170-30-3

[ 中文名 ]:
巴豆醛

[ 英文名 ]:
Crotonaldehyde

[中文别名 ]:

[英文别名 ]:

巴豆醛物理化学性质

[ 密度 ]:
0.8±0.1 g/cm3

[ 沸点 ]:
104.0±0.0 °C at 760 mmHg

[ 熔点 ]:
-76ºC

[ 分子式 ]:
C4H6O

[ 分子量 ]:
70.090

[ 闪点 ]:
4.6±4.3 °C

[ 精确质量 ]:
70.041862

[ PSA ]:
17.07000

[ LogP ]:
0.51

[ 外观性状 ]:
无色液体

[ 蒸汽密度 ]:
2.41 (vs air)

[ 蒸汽压 ]:
31.4±0.1 mmHg at 25°C

[ 折射率 ]:
1.402

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类分开存放

巴豆醛MSDS

巴豆醛毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GP9499000
CHEMICAL NAME :
Crotonaldehyde
CAS REGISTRY NUMBER :
4170-30-3
LAST UPDATED :
199806
DATA ITEMS CITED :
45
MOLECULAR FORMULA :
C4-H6-O
MOLECULAR WEIGHT :
70.10

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Cardiac - pulse rate increase, without fall in BP Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
104 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
580 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Blood - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
380 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
30 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 mg/m3/7H/8W-I
TOXIC EFFECTS :
Liver - other changes Liver - changes in liver weight Biochemical - Metabolism (Intermediary) - other proteins
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2664 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
TYPE OF TEST :
Sex chromosome loss and nondisjunction
TYPE OF TEST :
Heritable translocation test

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
21500 mg/L/16H
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,990,1984 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 5.7 mg/m3 (2 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 63,373,1995 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 63,373,1995 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 63,373,1995 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 2 ppm (6 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,62,1971 OSHA PEL (Gen Indu):8H TWA 2 ppm (6 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 2 ppm (6 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 2 ppm (6 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 2 ppm (6 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 2 ppm (6 mg/m3) JAN 1993 OEL-BELGIUM:TWA 2 ppm (5.7 mg/m3) JAN 1993 OEL-DENMARK:TWA 2 ppm (6 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 2 ppm (6 mg/m3);STEL 6 ppm (17 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 2 ppm (6 mg/m3) JAN 1993 OEL-GERMANY;Skin;Carcinogen JAN 1993 OEL-THE NETHERLANDS:TWA 2 ppm (6 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 2 ppm (6 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 2 ppm (6 mg/m3);Skin JAN 1993 OEL-UNITED KINGDOM:TWA 2 ppm (6 mg/m3);STEL 6 ppm (18 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6304 No. of Facilities: 6 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 387 (estimated) No. of Female Employees: 17 (estimated)
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巴豆醛安全信息

[ 符号 ]:

GHS02, GHS05, GHS06, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H301 + H311-H315-H318-H330-H335-H341-H373-H410

[ 警示性声明 ]:
P210-P260-P273-P280-P284-P301 + P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F;T+;N

[ 风险声明 (欧洲) ]:
11-24/25-26-37/38-41-48/22-50-68

[ 安全声明 (欧洲) ]:
26-28-36/37/39-45-61

[ 危险品运输编码 ]:
UN 1143 6.1/PG 1

[ WGK德国 ]:
3

[ RTECS号 ]:
GP9625000

[ 包装等级 ]:
I

[ 危险类别 ]:
6.1(a)

巴豆醛制备

1.纯巴豆醛容易树脂化,在空气中逐渐氧化生成巴豆酸。

2.由二分子乙醛缩合而成。

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巴豆醛文献

Methyl vinyl ketone, a toxic ingredient in cigarette smoke extract, modifies glutathione in mouse melanoma cells.

Chem. Pharm. Bull. 62(8) , 772-8, (2014)

Cigarette smoke contains many harmful chemicals, which contribute to the pathogenesis of smoking-related diseases such as chronic obstructive pulmonary disease, cancer and cardiovascular disease. The ...

Purity Determination of Acetaldehyde in an Acetaldehyde Certified Reference Material.

Anal. Sci. 31 , 463-8, (2015)

Acetaldehyde is regulated as a toxic substance in various fields, and the method for monitoring or analysis of acetaldehyde is important. However, handling is difficult because of the high reactivity ...

Cigarette smoke has sensory effects through nicotinic and TRPA1 but not TRPV1 receptors on the isolated mouse trachea and larynx.

Am. J. Physiol. Lung Cell. Mol. Physiol. 309 , L812-20, (2015)

Cigarette smoke (CS) exposes chemosensory nerves in the airways to a multitude of chemicals, some acting through the irritant receptors TRPV1 and TRPA1 but potentially also through nicotinic acetylcho...


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【巴豆醛】化源网提供巴豆醛CAS号4170-30-3,巴豆醛MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询巴豆醛上化源网,专业又轻松。>>电脑版:巴豆醛

标题:巴豆醛_MSDS_用途_密度_巴豆醛CAS号【4170-30-3】_化源网 地址:https://m.chemsrc.com/mip/cas/4170-30-3_250384.html