o-(4-BIS(β-CHLOROETHYL)AMINO-o-TOLYL-AZO) BENZOIC ACID

名称

[ CAS 号 ]:
4213-40-5

[ 英文名 ]:
o-(4-BIS(β-CHLOROETHYL)AMINO-o-TOLYL-AZO) BENZOIC ACID

[英文别名 ]:

2'-Carboxy-2-methylphenylazo nitrogen mustard
Azo-mustard
CB 1414

物理化学性质

[ 密度 ]:
1.27g/cm3

[ 沸点 ]:
591.8ºC at 760 mmHg

[ 分子式 ]:
C₁₈H₁₉Cl₂N₃O₂

[ 分子量 ]:
380.26800

[ 精确质量 ]:
379.08500

[ PSA ]:
65.26000

[ LogP ]:
5.39260

[ 折射率 ]:
1.594

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG4425000

CHEMICAL NAME :: Benzoic acid, 2-(4-bis(2-chloroethyl)amino-2-methyl)phenylazo-

CAS REGISTRY NUMBER :: 4213-40-5

BEILSTEIN REFERENCE NO. :: 3443540

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C18-H19-Cl2-N3-O2

MOLECULAR WEIGHT :: 380.30

WISWESSER LINE NOTATION :: QVR BNUNR B1 DN2G2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 50,243,1973

TYPE OF TEST :: LD10 - Lethal Dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 17,56,1962

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 950 ug/kg

TOXIC EFFECTS :: Gastrointestinal - other changes Blood - leukopenia Blood - thrombocytopenia

REFERENCE :: CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,202,1965

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 950 ug/kg

TOXIC EFFECTS :: Blood - leukopenia Blood - thrombocytopenia Blood - other changes

REFERENCE :: CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,202,1965

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安全信息

[ 海关编码 ]:
2927000090

海关

[ 海关编码 ]: 2927000090

[ 中文概述 ]:
2927000090 其他重氮化合物、偶氮化合物等（包括氧化偶氮化合物）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%