alpha.-Allylphenethylamine hydrochloride
alpha.-Allylphenethylamine hydrochloride名称
[ CAS 号 ]:
4255-24-7
[ 英文名 ]:
alpha.-Allylphenethylamine hydrochloride
[英文别名 ]:
- Aletamine HCl
- Aletamine hydrochloride [USAN]
- Ethylamine,1-allyl-2-phenyl-,hydrochloride
- NDR 5061A
- ALETAMINE HYDROCHLORIDE
alpha.-Allylphenethylamine hydrochloride物理化学性质
[ 沸点 ]:
249.2ºC at 760 mmHg
[ 分子式 ]:
C11H16ClN
[ 分子量 ]:
197.70400
[ 闪点 ]:
103.6ºC
[ 精确质量 ]:
197.09700
[ PSA ]:
26.02000
[ LogP ]:
3.63480
alpha.-Allylphenethylamine hydrochloride毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SG9275000
- CHEMICAL NAME :
- Phenethylamine, alpha-allyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 4255-24-7
- LAST UPDATED :
- 199112
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C11-H15-N.Cl-H
- MOLECULAR WEIGHT :
- 197.73
- WISWESSER LINE NOTATION :
- 1U2YZ1R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 680 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 172,251,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in psychophysiological tests
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 159,442,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 43 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 172,251,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 175 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 172,251,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 260 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JNDRAK Journal of New Drugs. (Albany, NY) V.1-6, 1961-66. For publisher information, see JCPCBR. Volume(issue)/page/year: 6,96,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,332,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 172 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 172,251,1968
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