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(S)-2-甲基脯氨酸

(S)-2-甲基脯氨酸用途

(S) -2-甲基吡咯烷-2-羧酸是脯氨酸衍生物[1]。

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(S)-2-甲基脯氨酸名称

[ CAS 号 ]:
42856-71-3

[ 中文名 ]:
α-甲基-L-脯氨酸

[ 英文名 ]:
2-Methyl-L-proline

[中文别名 ]:

[英文别名 ]:

MFCD01318647
α-Methyl-L-proline
L-Proline, 2-methyl-
2-Methyl-L-proline
(S)-2-Methyl proline

(S)-2-甲基脯氨酸生物活性

[ 描述 ]:

(S) -2-甲基吡咯烷-2-羧酸是脯氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

(S)-2-甲基脯氨酸物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
241.9±33.0 °C at 760 mmHg

[ 熔点 ]:
310 °C

[ 分子式 ]:
C₆H₁₁NO₂

[ 分子量 ]:
129.157

[ 闪点 ]:
100.1±25.4 °C

[ 精确质量 ]:
129.078979

[ PSA ]:
49.33000

[ LogP ]:
-0.03

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.475

[ 储存条件 ]:
-15°C

[ 水溶解性 ]:
可溶于：甲醇

(S)-2-甲基脯氨酸MSDS

(S)-2-甲基脯氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933990090

(S)-2-甲基脯氨酸合成路线

(S)-2-甲基脯氨酸上下游产品

(S)-2-甲基脯氨酸上游产品

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(S)-2-甲基脯氨酸海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

(S)-2-甲基脯氨酸文献

Effects of ring contraction on the conformational preferences of α-substituted proline analogs.

Biopolymers 98(2) , 98-110, (2012)

The structural consequences derived from the incorporation of either a methyl or a phenyl group at the α carbon of proline were recently investigated by quantum mechanical calculations (J Org Chem 200...

Beta-turns induced in bradykinin by (S)-alpha-methylproline.

FEBS Lett. 297(3) , 216-20, (1992)

The ability of (S)-alpha-methylproline (alpha-MePro) to stabilise reverse-turn conformations in the peptide hormone bradykinin (BK = Arg1-Pro2-Pro3-Gly4-Phe5-Ser6-Pro7-Phe8-Arg9) has been investigated...

alpha-Methylproline-containing renin inhibitory peptides: in vivo evaluation in an anesthetized, ganglion-blocked, hog renin infused rat model.

J. Med. Chem. 30(3) , 536-41, (1987)

A structure-activity analysis of peptides containing backbone C alpha-methyl modification at the P4 site of the angiotensinogen sequence led to the discovery of potent renin inhibitors with apparent i...

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