7-(2-(ETHYL-2-CHLOROETHYL)AMINOETHYL-AMINO)BENZ(c)-ACRIDINE DIHYDRO-CHLORIDE

名称

[ CAS 号 ]:
4310-69-4

[ 英文名 ]:
7-(2-(ETHYL-2-CHLOROETHYL)AMINOETHYL-AMINO)BENZ(c)-ACRIDINE DIHYDRO-CHLORIDE

[英文别名 ]:

ICR 311

物理化学性质

[ 密度 ]:
1.236g/cm3

[ 沸点 ]:
556.8ºC at 760 mmHg

[ 分子式 ]:
C₂₃H₂₅Cl₂N₃

[ 分子量 ]:
414.37100

[ 闪点 ]:
290.5ºC

[ 精确质量 ]:
413.14300

[ PSA ]:
28.16000

[ LogP ]:
6.38880

[ 折射率 ]:
1.708

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CU3440000

CHEMICAL NAME :: Benz(c)acridine, 7-(2-(2-chloroethylethylamino)ethylamino)-, dihydrochloride

CAS REGISTRY NUMBER :: 4310-69-4

LAST UPDATED :: 199109

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C23-H24-Cl-N3.2Cl-H

MOLECULAR WEIGHT :: 450.87

WISWESSER LINE NOTATION :: T D6 C666 BNJ MM2N2&2G &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD20 - Lethal Dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3823 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,739,1972

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 36,2423,1976 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4500 ug/kg

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 36,2423,1976

点击显示