(+)-白屈菜碱盐酸盐

(+)-白屈菜碱盐酸盐名称

[ 英文名 ]:
[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-13-methyl-, hydrochloride (1:1), (5bR,6S,12bS)-

[英文别名 ]:

(+)-ChelidonineHCl
CHELIDONINE HYDROCHLORIDE

(+)-白屈菜碱盐酸盐物理化学性质

[ 密度 ]:
1.422 g/cm3

[ 沸点 ]:
507.4ºC at 760 mmHg

[ 熔点 ]:
275-283ºC

[ 分子式 ]:
C₂₀H₂₀ClNO₅

[ 分子量 ]:
389.83000

[ 闪点 ]:
260.7ºC

[ 精确质量 ]:
389.10300

[ PSA ]:
60.39000

[ LogP ]:
3.07120

(+)-白屈菜碱盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FL9450500

CHEMICAL NAME :: Chelidonine, hydrochloride

CAS REGISTRY NUMBER :: 4312-31-6

LAST UPDATED :: 199109

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H19-N-O5.Cl-H

MOLECULAR WEIGHT :: 389.86

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 41,125,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1300 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 41,125,1989

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(+)-白屈菜碱盐酸盐安全信息

[ 海关编码 ]:
2933990090

(+)-白屈菜碱盐酸盐海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%