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Z-PHE-LEU-OH

Z-PHE-LEU-OH用途

Z-Phe-Leu-OH(NSC 334018)是羧肽酶Y(CPY)的底物。Z-Phe-Leu-OH与重组CPY孵育以测定肽酶活性[1]。

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Z-PHE-LEU-OH名称

[ CAS 号 ]:
4313-73-9

[ 中文名 ]:
Z-PHE-LEU-OH

[ 英文名 ]:
Z-Phe-Leu

[中文别名 ]:

[英文别名 ]:

Cbz-L-Phe-L-Leu-OH
Z-Phe-Leu
N-CBZ-Phe-Leu
N-Benzyloxycarbonyl-L-phenylalanyl-L-leucin
Z-Phe-Leu-OH
Cbz-Phe-Leu-OH

Z-PHE-LEU-OH生物活性

[ 描述 ]:

Z-Phe-Leu-OH(NSC 334018)是羧肽酶Y(CPY)的底物。Z-Phe-Leu-OH与重组CPY孵育以测定肽酶活性[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Makino M, et, al. Carboxypeptidase Y activity and maintenance is modulated by a large helical structure. FEBS Open Bio. 2019 Jul;9(7):1337-1343.

Z-PHE-LEU-OH物理化学性质

[ 密度 ]:
1.193g/cm3

[ 沸点 ]:
674.4ºC at 760mmHg

[ 分子式 ]:
C₂₃H₂₈N₂O₅

[ 分子量 ]:
412.47900

[ 闪点 ]:
361.7ºC

[ 精确质量 ]:
412.20000

[ PSA ]:
104.73000

[ LogP ]:
3.92140

[ 折射率 ]:
1.564

[ 储存条件 ]:
-20°C

Z-PHE-LEU-OHMSDS

详细MSDS(安全技术说明书)

Z-PHE-LEU-OH安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

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Z-PHE-LEU-OH文献

Amphipathic property of free thiol group contributes to an increase in the catalytic efficiency of carboxypeptidase Y.

Eur. J. Biochem. 269 , 3220-3225, (2002)

Cys341 of carboxypeptidase Y, which constitutes one side of the solvent-accessible surface of the S1 binding pocket, was replaced with Gly, Ser, Asp, Val, Phe or His by site-directed mutagenesis. Kine...

Debittering effect of Actinomucor elegans peptidases on soybean protein hydrolysates.

J. Ind. Microbiol. Biotechnol. 35 , 41-47, (2008)

Effects of the enzymes in Actinomucor elegans extract and the enzyme Alcalase 2.4L on debittering the soybean protein hydrolysates were investigated. When the protein was treated only with the latter,...

Characterization of a bifunctional aminoacylase/carboxypeptidase from radioresistant bacterium Deinococcus radiodurans R1.

J. Biotechnol. 128 , 322-334, (2007)

The gene encoding a Deinococcus radiodurans R1 bifunctional aminoacylase/carboxypeptidase (DR_ACY/CP) was amplified by polymerase chain reaction and cloned into pQE-30 to generate pQE-DRAC. The cloned...

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