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4-丁氧基苯胺

4-丁氧基苯胺用途

【用途一】
医药中间体。

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4-丁氧基苯胺名称

[ CAS 号 ]:
4344-55-2

[ 中文名 ]:
4-丁氧基苯胺

[ 英文名 ]:
4-Butoxyanilin

[中文别名 ]:

[英文别名 ]:

4-Butyloxybenzenamine
4-Butoxyanilin
MFCD00007866
4-Butoxyaniline
Benzenamine, 4-butoxy-
p-Butoxyaniline
EINECS 224-402-2

4-丁氧基苯胺物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
278.0±13.0 °C at 760 mmHg

[ 分子式 ]:
C₁₀H₁₅NO

[ 分子量 ]:
165.232

[ 闪点 ]:
123.6±13.1 °C

[ 精确质量 ]:
165.115356

[ PSA ]:
35.25000

[ LogP ]:
2.34

[ 外观性状 ]:
透明暗棕色液体

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.530

[ 储存条件 ]:
室温，干燥

4-丁氧基苯胺MSDS

4-丁氧基苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BW9420000

CHEMICAL NAME :: Aniline, p-butoxy-

CAS REGISTRY NUMBER :: 4344-55-2

BEILSTEIN REFERENCE NO. :: 2084421

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H15-N-O

MOLECULAR WEIGHT :: 165.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 89,153,1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 52,215,1956

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4-丁氧基苯胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302 + H312 + H332-H315-H319-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S28-S36/37/39-S45

[ 危险品运输编码 ]:
2810

[ WGK德国 ]:
3

[ RTECS号 ]:
BW9420000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2922299090

4-丁氧基苯胺合成路线

4-丁氧基苯胺制备

由对硝基酚钠经烃化、还原而得。1.烃化将对硝基酚钠、溴丁烷加入乙醇中加热回流，反应4h后，加压保温反应16h。然后降温至75℃以下过滤，滤液回收乙醇，剩余液经水洗涤，分去水分，得油状对硝基苯丁醚。2.还原先将硫磺、硫化钠加入水中加热溶解，分次将对硝基苯丁醚加入，在138-140℃保温反应16h。降温至130℃以下，加水搅拌后静置分层。水层弃去，将油层过滤后减压蒸馏，收集144-146℃（1.33kPa）馏分，得对氨基苯丁醚。

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4-丁氧基苯胺海关

[ 海关编码 ]: 2922299090

[ 中文概述 ]:
2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

4-丁氧基苯胺文献

6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors.

J. Med. Chem. 52 , 5044-57, (2009)

Following a ligand-based drug design approach, a potent mixed formyl peptide receptor 1 (FPR1) and formyl peptide receptor-like 1 (FPRL1) agonist (14a) and a potent and specific FPRL1 agonist (14x) we...

Alkali metal cation cooperative anion recognition by heteroditopic bis (calix [4] arene) rhenium (I) bipyridyl and ferrocene receptor molecules. Cooper JB, et al.

J. Chem. Soc., Dalton Trans. 16 , 2721-2728, (2000)

Low-Pressure Hydrogenation of Alkoxyanilines with Noble Metal Catalysts. Freifelder M, et al.

J. Org. Chem. 30(7) , 2485-86, (1965)

更多文献

4-丁氧基苯胺

4-丁氧基苯胺用途

4-丁氧基苯胺名称

4-丁氧基苯胺物理化学性质

4-丁氧基苯胺MSDS

详细MSDS(安全技术说明书)

4-丁氧基苯胺毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

4-丁氧基苯胺安全信息

4-丁氧基苯胺合成路线

详细合成路线

4-丁氧基苯胺制备

4-丁氧基苯胺海关

4-丁氧基苯胺文献

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