UNII:DLM851L3RD

UNII:DLM851L3RD用途

(S)-AM1241 binds to cannabinoid (CB) receptors and is selective for CB2 over CB1. (S)-1241 acts as an agonist at human, rat, and mouse CB2 receptors but shows greater activity at human CB2 than at rat and mouse CB2 receptors. Similar to the racemate AM1241, (S)-AM1241 produces antinociception to thermal pain but not mechanical pain in rats. The pain-reducing effect of (S)-AM1241 is blocked by the CB2-specific inhibitor SR 144528 but not by either the CB1-selective inhibitor rimonabant or the opioid receptor blocker naloxone
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UNII:DLM851L3RD名称

[ CAS 号 ]:
444912-53-2

[ 英文名 ]:
UNII:DLM851L3RD

[英文别名 ]:

UNII:DLM851L3RD物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
630.7±55.0 °C at 760 mmHg

[ 分子式 ]:
C22H22IN3O3

[ 分子量 ]:
503.333

[ 闪点 ]:
335.2±31.5 °C

[ 精确质量 ]:
503.070587

[ PSA ]:
71.06000

[ LogP ]:
4.85

[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C

[ 折射率 ]:
1.696

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标题:444912-53-2_UNII:DLM851L3RDCAS号:444912-53-2_UNII:DLM851L3RD【结构式 性质 英文】 - 化源网 地址:https://m.chemsrc.com/mip/cas/444912-53-2_452570.html