N-2,5-DIIODOBENZOYL-N′,N′,N″,N″-DIETHYL-ENEPHOSPHORTRIAMIDE

名称

[ CAS 号 ]:
4460-32-6

[ 英文名 ]:
N-2,5-DIIODOBENZOYL-N′,N′,N″,N″-DIETHYL-ENEPHOSPHORTRIAMIDE

[英文别名 ]:

Diiodbenzoteph
Dijodbenzotef
Diiodobenzoteph
Diiodobenzotef
Diiodobenzotepa
2,5-Diodobenzo-TEPA

物理化学性质

[ 密度 ]:
2.31g/cm3

[ 分子式 ]:
C₁₁H₁₂I₂N₃O₂P

[ 分子量 ]:
503.01500

[ 精确质量 ]:
502.87600

[ PSA ]:
62.00000

[ LogP ]:
2.63160

[ 折射率 ]:
1.765

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV2352000

CHEMICAL NAME :: Benzamide, N-(bis(1-aziridinyl)phosphinyl)-2,5-diiodo-

CAS REGISTRY NUMBER :: 4460-32-6

BEILSTEIN REFERENCE NO. :: 1324621

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C11-H12-I2-N3-O2-P

MOLECULAR WEIGHT :: 503.03

WISWESSER LINE NOTATION :: T3NTJ APO&MVR BI EI&- AT3NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 12,689,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 41,135,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness

REFERENCE :: FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 7,91,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 850 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,626,1982

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安全信息

[ 海关编码 ]:
2933990090

海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%