ALPHA-羟基-苯乙胺盐酸盐
ALPHA-羟基-苯乙胺盐酸盐名称
[ CAS 号 ]:
4561-43-7
[ 中文名 ]:
ALPHA-羟基-苯乙胺盐酸盐
[ 英文名 ]:
2-Amino-1-phenylethanol hydrochloride
[英文别名 ]:
- (+-)-2-amino-1-phenyl-ethanol,hydrochloride
- 2-Amino-1-phenyl-butandion-(1,3)
- Benzeneethanaminium, β-hydroxy-, chloride (1:1)
- (+-)-2-Amino-1-phenyl-aethanol,Hydrochlorid
- 1,3-Butanedione,2-amino-1-phenyl
- amino-2 phenyl-1 ethanol chlorhydrate
- β-Hydroxyphenethylamine, hydrochloride
- 2-Hydroxy-2-phenylethanaminium chloride
- 2-Amino-1-phenylethanol hydrochloride (1:1)
- β-Phenyl-β-hydroxy-ethylamine, hydrochloride
ALPHA-羟基-苯乙胺盐酸盐物理化学性质
[ 沸点 ]:
283.5ºC at 760 mmHg
[ 分子式 ]:
C8H12ClNO
[ 分子量 ]:
173.640
[ 闪点 ]:
125.3ºC
[ 精确质量 ]:
173.060745
[ PSA ]:
46.25000
[ LogP ]:
2.18100
ALPHA-羟基-苯乙胺盐酸盐毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DN7175000
- CHEMICAL NAME :
- Benzyl alcohol, alpha-(aminomethyl)-, hydrochloride
- CAS REGISTRY NUMBER :
- 4561-43-7
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C8-H11-N-O.Cl-H
- MOLECULAR WEIGHT :
- 173.66
- WISWESSER LINE NOTATION :
- Z1YQR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 71,62,1941
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 9,203,1936
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 520 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 237,171,1959
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 275 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 9,203,1936
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 38 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 32,121,1927
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 886 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 32,121,1927 *** REVIEWS *** TOXICOLOGY REVIEW CHREAY Chemical Reviews. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1924- Volume(issue)/page/year: 9,389,1931
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